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    Panama Canal
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  • Adults (25+)
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258 Cruises

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  • 14-Night Panama Canal Cruise

    14-Night Panama Canal Cruise
    Norwegian Cruise Line
    Norwegian Star
    Depart: Sat, Mar 30, 2019
    Returns: Sat, Apr 13, 2019
    Depart – Los Angeles, California
    • At Sea
    • Cabo San Lucas, Mexico
    • At Sea
    • Acapulco, Mexico
    • At Sea
    • Puerto Quetzal, Guatemala
    • San Juan del Sur, Nicaragua
    • Puntarenas, Costa Rica
    • At Sea
    • Panama Canal
    • Cartagena, Colombia
    • At Sea
    • At Sea
    Returns – Miami, Florida
    Los Angeles, California - At Sea - Cabo San Lucas, Mexico - At Sea - Acapulco, Mexico - At Sea - Puerto Quetzal, Guatemala - San Juan del Sur, Nicaragua - Puntarenas, Costa Rica - At Sea - Panama Canal - Cartagena, Colombia - At Sea - At Sea - Miami, Florida
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • Reduced Deposit - Only pay $50 per person
    from
    $699* USD
    *restrictions apply


  • 11-Night Panama Canal Cruise

    up to
    $50
    CREDIT*
    11-Night Panama Canal Cruise
    Norwegian Cruise Line
    Norwegian Pearl
    Depart: Mon, Nov 11, 2019
    Returns: Fri, Nov 22, 2019
    Depart – Miami, Florida
    • At Sea
    • At Sea
    • Cartagena, Colombia
    • Panama Canal
    • Colon, Panama
    • Puerto Limon, Costa Rica
    • At Sea
    • Harvest Caye, Belize
    • Roatan, Honduras
    • Costa Maya, Mexico
    • At Sea
    Returns – Miami, Florida
    Miami, Florida - At Sea - At Sea - Cartagena, Colombia - Panama Canal - Colon, Panama - Puerto Limon, Costa Rica - At Sea - Harvest Caye, Belize - Roatan, Honduras - Costa Maya, Mexico - At Sea - Miami, Florida
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • FREE WiFi Package - Ends 3/26
    • FREE Drinks, Dining, Excursion Credit & WiFi - Ends 3/26
    • FREE Drinks, 3rd/4th FREE - Ends 3/26
    • show more 
    from
    $749* USD
    *restrictions apply
  • 12-Night Panama Canal Cruise

    up to
    $50
    CREDIT*
    12-Night Panama Canal Cruise
    Norwegian Cruise Line
    Norwegian Pearl
    Depart: Fri, Nov 22, 2019
    Returns: Wed, Dec 4, 2019
    Depart – Miami, Florida
    • At Sea
    • At Sea
    • Cartagena, Colombia
    • Panama Canal
    • Colon, Panama
    • Puerto Limon, Costa Rica
    • At Sea
    • Roatan, Honduras
    • Harvest Caye, Belize
    • Costa Maya, Mexico
    • At Sea
    • Great Stirrup Cay, Bahamas
    Returns – Miami, Florida
    Miami, Florida - At Sea - At Sea - Cartagena, Colombia - Panama Canal - Colon, Panama - Puerto Limon, Costa Rica - At Sea - Roatan, Honduras - Harvest Caye, Belize - Costa Maya, Mexico - At Sea - Great Stirrup Cay, Bahamas - Miami, Florida
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • FREE WiFi Package - Ends 3/26
    • FREE Drinks, Dining, Excursion Credit & WiFi - Ends 3/26
    • FREE Drinks, 3rd/4th FREE - Ends 3/26
    • show more 
    from
    $899* USD
    *restrictions apply
  • 14-Night Panama Canal Cruise

    up to
    $50
    CREDIT*
    14-Night Panama Canal Cruise
    Norwegian Cruise Line
    Norwegian Dawn
    Depart: Sun, Dec 1, 2019
    Returns: Sun, Dec 15, 2019
    Depart – Tampa, Florida
    • Key West, Florida
    • At Sea
    • Falmouth, Jamaica
    • At Sea
    • Santa Marta, Colombia
    • Cartagena, Colombia
    • Panama Canal
    • Colon, Panama
    • Puerto Limon, Costa Rica
    • At Sea
    • Roatan, Honduras
    • Harvest Caye, Belize
    • Costa Maya, Mexico
    • At Sea
    Returns – Tampa, Florida
    Tampa, Florida - Key West, Florida - At Sea - Falmouth, Jamaica - At Sea - Santa Marta, Colombia - Cartagena, Colombia - Panama Canal - Colon, Panama - Puerto Limon, Costa Rica - At Sea - Roatan, Honduras - Harvest Caye, Belize - Costa Maya, Mexico - At Sea - Tampa, Florida
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • FREE WiFi Package - Ends 3/26
    • FREE Drinks, Dining, Excursion Credit & WiFi - Ends 3/26
    • FREE Drinks and WiFi - Ends 3/26
    • show more 
    from
    $1,149* USD
    *restrictions apply
  • 15-Night Panama Canal Cruise

    up to
    $50
    CREDIT*
    15-Night Panama Canal Cruise
    Norwegian Cruise Line
    Norwegian Dawn
    Depart: Sat, Nov 9, 2019
    Returns: Sun, Nov 24, 2019
    Depart – New York, New York
    • At Sea
    • At Sea
    • At Sea
    • Willemstad, Curacao, Netherlands Antilles
    • Oranjestad, Aruba
    • Santa Marta, Colombia
    • Cartagena, Colombia
    • Panama Canal
    • Colon, Panama
    • Puerto Limon, Costa Rica
    • At Sea
    • Roatan, Honduras
    • Harvest Caye, Belize
    • Costa Maya, Mexico
    • At Sea
    Returns – Tampa, Florida
    New York, New York - At Sea - At Sea - At Sea - Willemstad, Curacao- Oranjestad, Aruba - Santa Marta, Colombia - Cartagena, Colombia - Panama Canal - Colon, Panama - Puerto Limon, Costa Rica - At Sea - Roatan, Honduras - Harvest Caye, Belize - Costa Maya, Mexico - At Sea - Tampa, Florida
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • FREE WiFi Package - Ends 3/26
    • FREE Drinks, Dining, Excursion Credit & WiFi - Ends 3/26
    • FREE Drinks and WiFi - Ends 3/26
    • show more 
    from
    $1,029* USD
    *restrictions apply
  • 15-Night Panama Canal Cruise

    up to
    $50
    CREDIT*
    15-Night Panama Canal Cruise
    Norwegian Cruise Line
    Norwegian Star
    Depart: Fri, Dec 6, 2019
    Returns: Sat, Dec 21, 2019
    Depart – Miami, Florida
    • At Sea
    • At Sea
    • Santa Marta, Colombia
    • Cartagena, Colombia
    • Panama Canal
    • At Sea
    • At Sea
    • Salaverry, Peru
    • Callao, Peru
    • Pisco, Peru
    • At Sea
    • Arica, Chile
    • At Sea
    • Coquimbo, Chile
    Returns – San Antonio, Chile
    Miami, Florida - At Sea - At Sea - Santa Marta, Colombia - Cartagena, Colombia - Panama Canal - At Sea - At Sea - Salaverry, Peru - Callao, Peru - Pisco, Peru - At Sea - Arica, Chile - At Sea - Coquimbo, Chile - San Antonio, Chile
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • FREE WiFi Package - Ends 3/26
    • FREE Drinks, Dining, Excursion Credit & WiFi - Ends 3/26
    • FREE Drinks and WiFi - Ends 3/26
    • show more 
    from
    $899* USD
    *restrictions apply
  • 10-Night Panama Canal Cruise

    10-Night Panama Canal Cruise
    Princess Cruises
    Island Princess
    Depart: Sun, Oct 27, 2019
    Returns: Wed, Nov 6, 2019
    Depart – Fort Lauderdale, Florida
    • At Sea
    • Falmouth, Jamaica
    • At Sea
    • Cartagena, Colombia
    • Panama Canal
    • San Cristobal, Panama
    • Puerto Limon, Costa Rica
    • At Sea
    • Grand Cayman, Cayman Islands
    • At Sea
    Returns – Fort Lauderdale, Florida
    Fort Lauderdale, Florida - At Sea - Falmouth, Jamaica - At Sea - Cartagena, Colombia - Panama Canal - San Cristobal, Panama - Puerto Limon, Costa Rica - At Sea - Grand Cayman, Cayman Islands - At Sea - Fort Lauderdale, Florida
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • Come Back New Sale! FREE Upgrades, up to $500 Credit and more!
    • Come Back New Sale! FREE Upgrades, up to $500 Credit and more!
    from
    $949* USD
    *restrictions apply
  • 10-Night Panama Canal Cruise

    10-Night Panama Canal Cruise
    Princess Cruises
    Island Princess
    Depart: Sat, Nov 16, 2019
    Returns: Tue, Nov 26, 2019
    Depart – Fort Lauderdale, Florida
    • At Sea
    • Falmouth, Jamaica
    • At Sea
    • Cartagena, Colombia
    • Panama Canal
    • San Cristobal, Panama
    • Puerto Limon, Costa Rica
    • At Sea
    • Grand Cayman, Cayman Islands
    • At Sea
    Returns – Fort Lauderdale, Florida
    Fort Lauderdale, Florida - At Sea - Falmouth, Jamaica - At Sea - Cartagena, Colombia - Panama Canal - San Cristobal, Panama - Puerto Limon, Costa Rica - At Sea - Grand Cayman, Cayman Islands - At Sea - Fort Lauderdale, Florida
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • Come Back New Sale! FREE Upgrades, up to $500 Credit and more!
    • Come Back New Sale! FREE Upgrades, up to $500 Credit and more!
    from
    $939* USD
    *restrictions apply
  • 10-Night Panama Canal Cruise

    10-Night Panama Canal Cruise
    Princess Cruises
    Caribbean Princess
    Depart: Sat, Nov 30, 2019
    Returns: Tue, Dec 10, 2019
    Depart – Fort Lauderdale, Florida
    • At Sea
    • Falmouth, Jamaica
    • At Sea
    • Cartagena, Colombia
    • Panama Canal
    • San Cristobal, Panama
    • Puerto Limon, Costa Rica
    • At Sea
    • Grand Cayman, Cayman Islands
    • At Sea
    Returns – Fort Lauderdale, Florida
    Fort Lauderdale, Florida - At Sea - Falmouth, Jamaica - At Sea - Cartagena, Colombia - Panama Canal - San Cristobal, Panama - Puerto Limon, Costa Rica - At Sea - Grand Cayman, Cayman Islands - At Sea - Fort Lauderdale, Florida
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • Come Back New Sale! FREE Upgrades, up to $500 Credit and more!
    • Come Back New Sale! FREE Upgrades, up to $500 Credit and more!
    from
    $849* USD
    *restrictions apply
  • 10-Night Panama Canal Cruise

    10-Night Panama Canal Cruise
    Princess Cruises
    Island Princess
    Depart: Thu, Oct 17, 2019
    Returns: Sun, Oct 27, 2019
    Depart – Fort Lauderdale, Florida
    • At Sea
    • Falmouth, Jamaica
    • At Sea
    • Cartagena, Colombia
    • Panama Canal
    • San Cristobal, Panama
    • Puerto Limon, Costa Rica
    • At Sea
    • Grand Cayman, Cayman Islands
    • At Sea
    Returns – Fort Lauderdale, Florida
    Fort Lauderdale, Florida - At Sea - Falmouth, Jamaica - At Sea - Cartagena, Colombia - Panama Canal - San Cristobal, Panama - Puerto Limon, Costa Rica - At Sea - Grand Cayman, Cayman Islands - At Sea - Fort Lauderdale, Florida
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • Come Back New Sale! FREE Upgrades, up to $500 Credit and more!
    • Come Back New Sale! FREE Upgrades, up to $500 Credit and more!
    from
    $979* USD
    *restrictions apply

Terms & Conditions

*Expedia Extras offers are per stateroom (unless otherwise stated) on select sailings, based on double occupancy, apply to new bookings only, are not combinable with any other offer, are capacity controlled and may be withdrawn without notice. Certain restrictions may apply. For full terms and conditions, click the specific Expedia Extra offer or contact your Expedia CruiseShipCenters Vacation Consultant.

For Bookings Made in Quebec: Travel Agents’ Customers Compensation Fund FICAV (0.10% or 1$ per 1000$ of tourism products).

Prices are per person (based on 2 passengers in the same stateroom), cruise only in USD dollars. Airfare, transfers, taxes, fees and port expenses are additional (unless otherwise stated). Prices vary by ship, stateroom type and sailing date. Prices and offers are subject to availability and change without notice, and are capacity controlled. Fuel supplement may apply. Expedia CruiseShipCenters is not responsible for errors that may occur due to the transfer of information from selected third parties, technical error, or human error.

Our default sort order is based on a number of relevant factors such as cruise line rating, ship rating, price per day, origin rating, destination rating, length of cruise, and booking window.

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