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  • Destinations
    Panama Canal
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    Any Port
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  • Adults (25+)
    2

321 Cruises

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  • 14-Night Panama Canal Cruise

    14-Night Panama Canal Cruise
    Carnival Cruise Lines
    Carnival Glory
    Depart: Sun, Feb 9, 2020
    Returns: Sun, Feb 23, 2020
    Depart – New Orleans, Louisiana
    • At Sea
    • At Sea
    • Montego Bay, Jamaica
    • At Sea
    • Oranjestad, Aruba
    • Kralendijk, Bonaire, Netherlands Antilles
    • At Sea
    • Cartagena, Colombia
    • Panama Canal
    • Puerto Limon, Costa Rica
    • At Sea
    • Cozumel, Mexico
    • At Sea
    Returns – New Orleans, Louisiana
    New Orleans, Louisiana - At Sea - At Sea - Montego Bay, Jamaica - At Sea - Oranjestad, Aruba - Kralendijk, Bonaire- At Sea - Cartagena, Colombia - Panama Canal - Puerto Limon, Costa Rica - At Sea - Cozumel, Mexico - At Sea - New Orleans, Louisiana
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • Reduced Rates for a Limited Time!
    from
    $1,129* USD
    *restrictions apply
    Gov't fees & taxes from: $333/pp.


  • 10-Night Panama Canal Cruise

    10-Night Panama Canal Cruise
    Princess Cruises
    Island Princess
    Depart: Mon, Oct 7, 2019
    Returns: Thu, Oct 17, 2019
    Depart – Fort Lauderdale, Florida
    • At Sea
    • Amber Cove, Dominican Republic
    • At Sea
    • Cartagena, Colombia
    • Panama Canal
    • San Cristobal, Panama
    • Puerto Limon, Costa Rica
    • At Sea
    • Falmouth, Jamaica
    • At Sea
    Returns – Fort Lauderdale, Florida
    Fort Lauderdale, Florida - At Sea - Amber Cove, Dominican Republic - At Sea - Cartagena, Colombia - Panama Canal - San Cristobal, Panama - Puerto Limon, Costa Rica - At Sea - Falmouth, Jamaica - At Sea - Fort Lauderdale, Florida
    from
    $865* USD
    *restrictions apply
  • 8-Night Panama Canal Cruise

    8-Night Panama Canal Cruise
    Carnival Cruise Lines
    Carnival Legend
    Depart: Sat, Jan 9, 2021
    Returns: Sun, Jan 17, 2021
    Depart – Tampa, Florida
    • At Sea
    • At Sea
    • Puerto Limon, Costa Rica
    • Panama Canal
    • At Sea
    • Georgetown, Grand Cayman, Cayman Islands
    • At Sea
    Returns – Tampa, Florida
    Tampa, Florida - At Sea - At Sea - Puerto Limon, Costa Rica - Panama Canal - At Sea - Georgetown, Grand Cayman- At Sea - Tampa, Florida
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • Reduced Rates for a Limited Time!
    from
    $839* USD
    *restrictions apply
    Gov't fees & taxes from: $320/pp.
  • 10-Night Panama Canal Cruise

    up to
    $500
    CREDIT*
    10-Night Panama Canal Cruise
    Princess Cruises
    Crown Princess
    Depart: Tue, Dec 29, 2020
    Returns: Fri, Jan 8, 2021
    Depart – Fort Lauderdale, Florida
    • At Sea
    • Falmouth, Jamaica
    • At Sea
    • Cartagena, Colombia
    • Panama Canal
    • San Cristobal, Panama
    • Puerto Limon, Costa Rica
    • At Sea
    • Grand Cayman, Cayman Islands
    • At Sea
    Returns – Fort Lauderdale, Florida
    Fort Lauderdale, Florida - At Sea - Falmouth, Jamaica - At Sea - Cartagena, Colombia - Panama Canal - San Cristobal, Panama - Puerto Limon, Costa Rica - At Sea - Grand Cayman, Cayman Islands - At Sea - Fort Lauderdale, Florida
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • Landmark Sale - Receive up to a $500 Onboard Cash Credit!
    • Landmark Sale - Receive up to a $500 Onboard Cash Credit!
    • Non Refundable Deposit on select rates
    from
    $1,149* USD
    *restrictions apply
  • 16-Night Panama Canal Cruise

    up to
    $50
    CREDIT*
    16-Night Panama Canal Cruise
    Norwegian Cruise Line
    Norwegian Joy
    Depart: Fri, Nov 8, 2019
    Returns: Sun, Nov 24, 2019
    Depart – Miami, Florida
    • Great Stirrup Cay, Bahamas
    • At Sea
    • At Sea
    • Cartagena, Colombia
    • Panama Canal
    • At Sea
    • Caldera, Costa Rica
    • At Sea
    • Puerto Quetzal, Guatemala
    • At Sea
    • At Sea
    • Mazatlan, Mexico
    • Puerto Vallarta, Mexico
    • Cabo San Lucas, Mexico
    • At Sea
    Returns – Los Angeles, California
    Miami, Florida - Great Stirrup Cay, Bahamas - At Sea - At Sea - Cartagena, Colombia - Panama Canal - At Sea - Caldera, Costa Rica - At Sea - Puerto Quetzal, Guatemala - At Sea - At Sea - Mazatlan, Mexico - Puerto Vallarta, Mexico - Cabo San Lucas, Mexico - At Sea - Los Angeles, California
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • Reduced Deposit - Only pay $50 per person
    • $50 Onboard Cash Credit
    from
    $1,199* USD
    *restrictions apply
  • 12-Night Panama Canal Cruise

    up to
    $50
    CREDIT*
    12-Night Panama Canal Cruise
    Norwegian Cruise Line
    Norwegian Pearl
    Depart: Fri, Nov 22, 2019
    Returns: Wed, Dec 4, 2019
    Depart – Miami, Florida
    • At Sea
    • At Sea
    • Cartagena, Colombia
    • Panama Canal
    • Colon, Panama
    • Puerto Limon, Costa Rica
    • At Sea
    • Roatan, Honduras
    • Harvest Caye, Belize
    • Costa Maya, Mexico
    • At Sea
    • Great Stirrup Cay, Bahamas
    Returns – Miami, Florida
    Miami, Florida - At Sea - At Sea - Cartagena, Colombia - Panama Canal - Colon, Panama - Puerto Limon, Costa Rica - At Sea - Roatan, Honduras - Harvest Caye, Belize - Costa Maya, Mexico - At Sea - Great Stirrup Cay, Bahamas - Miami, Florida
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • Reduced Deposit - Only pay $50 per person
    • $50 Onboard Cash Credit
    from
    $1,109* USD
    *restrictions apply
  • 11-Night Panama Canal Cruise

    up to
    $100
    CREDIT*
    11-Night Panama Canal Cruise
    Norwegian Cruise Line
    Norwegian Pearl
    Depart: Mon, Nov 11, 2019
    Returns: Fri, Nov 22, 2019
    Depart – Miami, Florida
    • At Sea
    • At Sea
    • Cartagena, Colombia
    • Panama Canal
    • Colon, Panama
    • Puerto Limon, Costa Rica
    • At Sea
    • Harvest Caye, Belize
    • Roatan, Honduras
    • Costa Maya, Mexico
    • At Sea
    Returns – Miami, Florida
    Miami, Florida - At Sea - At Sea - Cartagena, Colombia - Panama Canal - Colon, Panama - Puerto Limon, Costa Rica - At Sea - Harvest Caye, Belize - Roatan, Honduras - Costa Maya, Mexico - At Sea - Miami, Florida
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • Flash Deals! Up to $100 Onboard Cash Credit on select sailings and rates!
    • Reduced Deposit - Only pay $50 per person
    • $50 Onboard Cash Credit
    from
    $849* USD
    *restrictions apply
  • 8-Night Panama Canal Cruise

    8-Night Panama Canal Cruise
    Carnival Cruise Lines
    Carnival Legend
    Depart: Sat, Jan 25, 2020
    Returns: Sun, Feb 2, 2020
    Depart – Tampa, Florida
    • At Sea
    • At Sea
    • Puerto Limon, Costa Rica
    • Panama Canal
    • At Sea
    • Georgetown, Grand Cayman, Cayman Islands
    • At Sea
    Returns – Tampa, Florida
    Tampa, Florida - At Sea - At Sea - Puerto Limon, Costa Rica - Panama Canal - At Sea - Georgetown, Grand Cayman- At Sea - Tampa, Florida
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • Reduced Rates for a Limited Time!
    from
    $919* USD
    *restrictions apply
    Gov't fees & taxes from: $316/pp.
  • 12-Night Panama Canal Cruise

    up to
    $50
    CREDIT*
    12-Night Panama Canal Cruise
    Norwegian Cruise Line
    Norwegian Joy
    Depart: Sun, Oct 27, 2019
    Returns: Fri, Nov 8, 2019
    Depart – Miami, Florida
    • Great Stirrup Cay, Bahamas
    • At Sea
    • At Sea
    • Cartagena, Colombia
    • Panama Canal
    • Colon, Panama
    • Puerto Limon, Costa Rica
    • At Sea
    • Roatan, Honduras
    • Harvest Caye, Belize
    • Costa Maya, Mexico
    • At Sea
    Returns – Miami, Florida
    Miami, Florida - Great Stirrup Cay, Bahamas - At Sea - At Sea - Cartagena, Colombia - Panama Canal - Colon, Panama - Puerto Limon, Costa Rica - At Sea - Roatan, Honduras - Harvest Caye, Belize - Costa Maya, Mexico - At Sea - Miami, Florida
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • Reduced Deposit - Only pay $50 per person
    • $50 Onboard Cash Credit
    from
    $949* USD
    *restrictions apply
  • 15-Night Panama Canal Cruise

    15-Night Panama Canal Cruise
    Norwegian Cruise Line
    Norwegian Dawn
    Depart: Sat, Nov 9, 2019
    Returns: Sun, Nov 24, 2019
    Depart – New York, New York
    • At Sea
    • At Sea
    • At Sea
    • Willemstad, Curacao, Netherlands Antilles
    • Oranjestad, Aruba
    • Santa Marta, Colombia
    • Cartagena, Colombia
    • Panama Canal
    • Colon, Panama
    • Puerto Limon, Costa Rica
    • At Sea
    • Roatan, Honduras
    • Harvest Caye, Belize
    • Costa Maya, Mexico
    • At Sea
    Returns – Tampa, Florida
    New York, New York - At Sea - At Sea - At Sea - Willemstad, Curacao- Oranjestad, Aruba - Santa Marta, Colombia - Cartagena, Colombia - Panama Canal - Colon, Panama - Puerto Limon, Costa Rica - At Sea - Roatan, Honduras - Harvest Caye, Belize - Costa Maya, Mexico - At Sea - Tampa, Florida
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • Reduced Deposit - Only pay $50 per person
    from
    $1,069* USD
    *restrictions apply
    Gov't fees & taxes from: $505/pp.

Terms & Conditions

*Expedia Extras offers are per stateroom (unless otherwise stated) on select sailings, based on double occupancy, apply to new bookings only, are not combinable with any other offer, are capacity controlled and may be withdrawn without notice. Certain restrictions may apply. For full terms and conditions, click the specific Expedia Extra offer or contact your Expedia CruiseShipCenters Vacation Consultant.

For Bookings Made in Quebec: Travel Agents’ Customers Compensation Fund FICAV (0.10% or 1$ per 1000$ of tourism products).

Prices are per person (based on 2 passengers in the same stateroom), cruise only in USD dollars. Airfare, transfers, taxes, fees and port expenses are additional (unless otherwise stated). Prices vary by ship, stateroom type and sailing date. Prices and offers are subject to availability and change without notice, and are capacity controlled. Fuel supplement may apply. Expedia CruiseShipCenters is not responsible for errors that may occur due to the transfer of information from selected third parties, technical error, or human error.

Our default sort order is based on a number of relevant factors such as cruise line rating, ship rating, price per day, origin rating, destination rating, length of cruise, and booking window.

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