469-712-7676

Sarah Stouder
Franchise Partner

Have a Future Cruise Credit?
Our Vacation Consultants are here to help you secure an incredible deal and take the stress out of planning your next cruise. Find out more
Have a Future Cruise Credit?
Our Vacation Consultants are here to help you secure an incredible deal and take the stress out of planning your next cruise. Find out more
  • Destinations
    Any Destination
  • Departure Ports
    Santos, Brazil
  • Departure Date Range
    Any Date
  • Adults (25+)
    2

14 Cruises

Show Search Filters
Loading
from
to

Questions? 469-712-7676

  • 7-Night South America Cruise

    7-Night South America Cruise
    MSC Cruises
    MSC Fantasia
    Depart: Sun, Feb 14, 2021
    Returns: Sun, Feb 21, 2021
    Depart – Santos, Brazil
    • At Sea
    • Punta del Este, Uruguay
    • Buenos Aires, Argentina
    • Buenos Aires, Argentina
    • Montevideo, Uruguay
    • At Sea
    Returns – Santos, Brazil
    Santos, Brazil - At Sea - Punta del Este, Uruguay - Buenos Aires, Argentina - Buenos Aires, Argentina - Montevideo, Uruguay - At Sea - Santos, Brazil
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • Reduced Deposit - Only $49 per person
    from
    $899* USD
    *restrictions apply
    Gov't fees & taxes from: $98/pp.


  • 21-Night Transatlantic Cruise

    21-Night Transatlantic Cruise
    MSC Cruises
    MSC Fantasia
    Depart: Sun, Mar 7, 2021
    Returns: Sun, Mar 28, 2021
    Depart – Santos, Brazil
    • Rio de Janeiro, Brazil
    • At Sea
    • Salvador, Brazil
    • At Sea
    • At Sea
    • At Sea
    • At Sea
    • At Sea
    • At Sea
    • Santa Cruz de Tenerife, Spain
    • Funchal, Madeira, Portugal
    • At Sea
    • Cadiz, Spain
    • Malaga, Spain
    • Palma de Mallorca, Spain
    • Palma de Mallorca, Spain
    • Civitavecchia (Rome), Italy
    • At Sea
    • Kotor, Montenegro
    • Zadar, Croatia
    Returns – Trieste, Italy
    Santos, Brazil - Rio de Janeiro, Brazil - At Sea - Salvador, Brazil - At Sea - At Sea - At Sea - At Sea - At Sea - At Sea - Santa Cruz de Tenerife, Spain - Funchal, Madeira- At Sea - Cadiz, Spain - Malaga, Spain - Palma de Mallorca, Spain - Palma de Mallorca, Spain - Civitavecchia (Rome), Italy - At Sea - Kotor, Montenegro - Zadar, Croatia - Trieste, Italy
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • Reduced Deposit - Only $49 per person
    from
    $1,049* USD
    *restrictions apply
    Gov't fees & taxes from: $322/pp.
  • 7-Night South America Cruise

    7-Night South America Cruise
    MSC Cruises
    MSC Fantasia
    Depart: Sun, Jan 31, 2021
    Returns: Sun, Feb 7, 2021
    Depart – Santos, Brazil
    • At Sea
    • Punta del Este, Uruguay
    • Buenos Aires, Argentina
    • Buenos Aires, Argentina
    • Montevideo, Uruguay
    • At Sea
    Returns – Santos, Brazil
    Santos, Brazil - At Sea - Punta del Este, Uruguay - Buenos Aires, Argentina - Buenos Aires, Argentina - Montevideo, Uruguay - At Sea - Santos, Brazil
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • Reduced Deposit - Only $49 per person
    from
    $679* USD
    *restrictions apply
    Gov't fees & taxes from: $98/pp.
  • 7-Night South America Cruise

    7-Night South America Cruise
    MSC Cruises
    MSC Fantasia
    Depart: Sun, Dec 13, 2020
    Returns: Sun, Dec 20, 2020
    Depart – Santos, Brazil
    • At Sea
    • Punta del Este, Uruguay
    • Buenos Aires, Argentina
    • Buenos Aires, Argentina
    • Montevideo, Uruguay
    • At Sea
    Returns – Santos, Brazil
    Santos, Brazil - At Sea - Punta del Este, Uruguay - Buenos Aires, Argentina - Buenos Aires, Argentina - Montevideo, Uruguay - At Sea - Santos, Brazil
    from
    $629* USD
    *restrictions apply
    Gov't fees & taxes from: $98/pp.
  • 7-Night South America Cruise

    7-Night South America Cruise
    MSC Cruises
    MSC Fantasia
    Depart: Sun, Feb 28, 2021
    Returns: Sun, Mar 7, 2021
    Depart – Santos, Brazil
    • At Sea
    • Punta del Este, Uruguay
    • Buenos Aires, Argentina
    • Buenos Aires, Argentina
    • Montevideo, Uruguay
    • At Sea
    Returns – Santos, Brazil
    Santos, Brazil - At Sea - Punta del Este, Uruguay - Buenos Aires, Argentina - Buenos Aires, Argentina - Montevideo, Uruguay - At Sea - Santos, Brazil
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • Reduced Deposit - Only $49 per person
    from
    $629* USD
    *restrictions apply
    Gov't fees & taxes from: $98/pp.
  • 7-Night South America Cruise

    7-Night South America Cruise
    MSC Cruises
    MSC Fantasia
    Depart: Sun, Dec 20, 2020
    Returns: Sun, Dec 27, 2020
    Depart – Santos, Brazil
    • At Sea
    • Montevideo, Uruguay
    • Buenos Aires, Argentina
    • Buenos Aires, Argentina
    • Punta del Este, Uruguay
    • At Sea
    Returns – Santos, Brazil
    Santos, Brazil - At Sea - Montevideo, Uruguay - Buenos Aires, Argentina - Buenos Aires, Argentina - Punta del Este, Uruguay - At Sea - Santos, Brazil
    from
    $739* USD
    *restrictions apply
    Gov't fees & taxes from: $98/pp.
  • 7-Night South America Cruise

    7-Night South America Cruise
    MSC Cruises
    MSC Fantasia
    Depart: Sun, Feb 7, 2021
    Returns: Sun, Feb 14, 2021
    Depart – Santos, Brazil
    • At Sea
    • Montevideo, Uruguay
    • Buenos Aires, Argentina
    • Buenos Aires, Argentina
    • Punta del Este, Uruguay
    • At Sea
    Returns – Santos, Brazil
    Santos, Brazil - At Sea - Montevideo, Uruguay - Buenos Aires, Argentina - Buenos Aires, Argentina - Punta del Este, Uruguay - At Sea - Santos, Brazil
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • Reduced Deposit - Only $49 per person
    from
    $679* USD
    *restrictions apply
    Gov't fees & taxes from: $98/pp.
  • 7-Night South America Cruise

    7-Night South America Cruise
    MSC Cruises
    MSC Fantasia
    Depart: Sun, Feb 21, 2021
    Returns: Sun, Feb 28, 2021
    Depart – Santos, Brazil
    • At Sea
    • Punta del Este, Uruguay
    • Buenos Aires, Argentina
    • Buenos Aires, Argentina
    • Montevideo, Uruguay
    • At Sea
    Returns – Santos, Brazil
    Santos, Brazil - At Sea - Punta del Este, Uruguay - Buenos Aires, Argentina - Buenos Aires, Argentina - Montevideo, Uruguay - At Sea - Santos, Brazil
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • Reduced Deposit - Only $49 per person
    from
    $679* USD
    *restrictions apply
    Gov't fees & taxes from: $98/pp.
  • 7-Night South America Cruise

    7-Night South America Cruise
    MSC Cruises
    MSC Fantasia
    Depart: Sun, Jan 3, 2021
    Returns: Sun, Jan 10, 2021
    Depart – Santos, Brazil
    • At Sea
    • Montevideo, Uruguay
    • Buenos Aires, Argentina
    • Buenos Aires, Argentina
    • Punta del Este, Uruguay
    • At Sea
    Returns – Santos, Brazil
    Santos, Brazil - At Sea - Montevideo, Uruguay - Buenos Aires, Argentina - Buenos Aires, Argentina - Punta del Este, Uruguay - At Sea - Santos, Brazil
    from
    $729* USD
    *restrictions apply
    Gov't fees & taxes from: $98/pp.
  • 7-Night South America Cruise

    7-Night South America Cruise
    MSC Cruises
    MSC Fantasia
    Depart: Sun, Jan 10, 2021
    Returns: Sun, Jan 17, 2021
    Depart – Santos, Brazil
    • At Sea
    • Punta del Este, Uruguay
    • Buenos Aires, Argentina
    • Buenos Aires, Argentina
    • Montevideo, Uruguay
    • At Sea
    Returns – Santos, Brazil
    Santos, Brazil - At Sea - Punta del Este, Uruguay - Buenos Aires, Argentina - Buenos Aires, Argentina - Montevideo, Uruguay - At Sea - Santos, Brazil
    from
    $729* USD
    *restrictions apply
    Gov't fees & taxes from: $98/pp.

Terms & Conditions

*Expedia Extras offers are per stateroom (unless otherwise stated) on select sailings, based on double occupancy, apply to new bookings only, are not combinable with any other offer, are capacity controlled and may be withdrawn without notice. Certain restrictions may apply. For full terms and conditions, click the specific Expedia Extra offer or contact your Expedia CruiseShipCenters Vacation Consultant.

Prices are per person (based on 2 passengers in the same stateroom), cruise only in USD dollars. Airfare, transfers, taxes, fees and port expenses are additional (unless otherwise stated). Prices vary by ship, stateroom type and sailing date. Prices and offers are subject to availability and change without notice, and are capacity controlled. Fuel supplement may apply. Expedia CruiseShipCenters is not responsible for errors that may occur due to the transfer of information from selected third parties, technical error, or human error.

Our default sort order is based on a number of relevant factors such as cruise line rating, ship rating, price per day, origin rating, destination rating, length of cruise, and booking window.

Our Promise


At Expedia CruiseShipCenters, we are navigators of spectacular vacation experiences. As part of the number one brand in travel, this is our promise to you:


Learn More 
  • Advice you can trust.

  • The best choice in prices.

  • Expedia Extras.

  • More than cruises.

  • Always there.


Sarah Stouder
Franchise Partner