1-800-603-5755

George Leppla
Cruise & Vacation Consultant

  • Destinations
    South America
  • Departure Ports
    Any Port
  • Departure Date Range
    Any Date
  • Adults (25+)
    2

400 Cruises

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  • 3-Night South America Cruise

    3-Night South America Cruise
    MSC Cruises
    MSC Seaview
    Depart: Fri, Mar 6, 2020
    Returns: Mon, Mar 9, 2020
    Depart – Santos, Brazil
    • Balneario Camboriu, Brazil
    • At Sea
    Returns – Santos, Brazil
    Santos, Brazil - Balneario Camboriu, Brazil - At Sea - Santos, Brazil
    from
    $539* USD
    *restrictions apply
    Gov't fees & taxes from: $52/pp.


  • 15-Night South America Cruise

    15-Night South America Cruise
    Celebrity Cruises
    Celebrity Eclipse
    Depart: Fri, Dec 6, 2019
    Returns: Sat, Dec 21, 2019
    Depart – San Antonio, Chile
    • At Sea
    • Puerto Montt, Chile
    • Chilean Fjords, Chile
    • Strait of Magellan, Chile
    • At Sea
    • Punta Arenas, Chile
    • Ushuaia, Argentina
    • Cape Horn, Chile
    • At Sea
    • Puerto Madryn, Argentina
    • At Sea
    • Punta del Este, Uruguay
    • Montevideo, Uruguay
    • Buenos Aires, Argentina
    Returns – Buenos Aires, Argentina
    San Antonio, Chile - At Sea - Puerto Montt, Chile - Chilean Fjords, Chile - Strait of Magellan, Chile - At Sea - Punta Arenas, Chile - Ushuaia, Argentina - Cape Horn, Chile - At Sea - Puerto Madryn, Argentina - At Sea - Punta del Este, Uruguay - Montevideo, Uruguay - Buenos Aires, Argentina - Buenos Aires, Argentina
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • Sail Your Way Savings Offer! Save up to $500 per stateroom!
    • Sail Plus! FREE Drinks & WiFi
    • Sail Plus! FREE Drinks & Tips
    • show more 
    from
    $1,089* USD
    *restrictions apply
    Gov't fees & taxes from: $306/pp.
  • 14-Night South America Cruise

    BEST
    VALUE*
    14-Night South America Cruise
    Norwegian Cruise Line
    Norwegian Star
    Depart: Sat, Dec 21, 2019
    Returns: Sat, Jan 4, 2020
    Depart – San Antonio, Chile
    • At Sea
    • Puerto Montt, Chile
    • Puerto Chacabuco, Chile
    • Chilean Fjords, Chile
    • At Sea
    • Strait of Magellan, Chile
    • Punta Arenas, Chile
    • Beagle Channel (Argentina/Chile)
    • Ushuaia, Argentina
    • Cape Horn, Chile
    • Port Stanley, Falkland Islands (Malvinas)
    • At Sea
    • Puerto Madryn, Argentina
    • At Sea
    • Montevideo, Uruguay
    Returns – Buenos Aires, Argentina
    San Antonio, Chile - At Sea - Puerto Montt, Chile - Puerto Chacabuco, Chile - Chilean Fjords, Chile - At Sea - Strait of Magellan, Chile - Punta Arenas, Chile - Beagle Channel (Argentina/Chile) - Ushuaia, Argentina - Cape Horn, Chile - Port Stanley, Falkland Islands (Malvinas) - At Sea - Puerto Madryn, Argentina - At Sea - Montevideo, Uruguay - Buenos Aires, Argentina
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • Take All Free! Open Bar, Dining, Excursions, WiFi - Ends 8/20
    • FREE WiFi & Excursion Credit - Ends 8/20
    • FREE WiFi Package - Ends 8/20
    • show more 
    from
    $1,399* USD
    *restrictions apply
    Gov't fees & taxes from: $366/pp.
  • 13-Night South America Cruise

    13-Night South America Cruise
    Azamara
    Azamara Pursuit
    Depart: Sun, Dec 8, 2019
    Returns: Sat, Dec 21, 2019
    Depart – Buenos Aires, Argentina
    • Montevideo, Uruguay
    • At Sea
    • At Sea
    • Santos, Brazil
    • Paraty, Brazil
    • Buzios, Brazil
    • Rio de Janeiro, Brazil
    • Rio de Janeiro, Brazil
    • Rio de Janeiro, Brazil
    • At Sea
    • At Sea
    • Punta del Este, Uruguay
    Returns – Buenos Aires, Argentina
    Buenos Aires, Argentina - Montevideo, Uruguay - At Sea - At Sea - Santos, Brazil - Paraty, Brazil - Buzios, Brazil - Rio de Janeiro, Brazil - Rio de Janeiro, Brazil - Rio de Janeiro, Brazil - At Sea - At Sea - Punta del Este, Uruguay - Buenos Aires, Argentina
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • Sail Into Savings - up to 30% Off per person
    from
    $1,399* USD
    *restrictions apply
    Gov't fees & taxes from: $410/pp.
  • 16-Night South America Cruise

    16-Night South America Cruise
    Celebrity Cruises
    Celebrity Eclipse
    Depart: Wed, Nov 20, 2019
    Returns: Fri, Dec 6, 2019
    Depart – Los Angeles, California
    • At Sea
    • Cabo San Lucas, Mexico
    • Puerto Vallarta, Mexico
    • At Sea
    • Huatulco, Mexico
    • At Sea
    • Caldera, Costa Rica
    • At Sea
    • Manta, Ecuador
    • At Sea
    • Lima, Peru
    • At Sea
    • Arica, Chile
    • At Sea
    • At Sea
    Returns – San Antonio, Chile
    Los Angeles, California - At Sea - Cabo San Lucas, Mexico - Puerto Vallarta, Mexico - At Sea - Huatulco, Mexico - At Sea - Caldera, Costa Rica - At Sea - Manta, Ecuador - At Sea - Lima, Peru - At Sea - Arica, Chile - At Sea - At Sea - San Antonio, Chile
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • Sail Your Way Savings Offer! Save up to $500 per stateroom!
    • Sail Plus! FREE Drinks & WiFi
    • Sail Plus! FREE Drinks & Tips
    • show more 
    from
    $1,249* USD
    *restrictions apply
    Gov't fees & taxes from: $214/pp.
  • 14-Night South America Cruise

    REDUCED
    DEPOSIT*
    14-Night South America Cruise
    Holland America Line
    ms Zaandam
    Depart: Wed, Dec 4, 2019
    Returns: Wed, Dec 18, 2019
    Depart – San Antonio, Chile
    • At Sea
    • Puerto Montt, Chile
    • Puerto Chacabuco, Chile
    • Chilean Fjords, Chile
    • Amalia Glacier, Chile
    • Strait of Magellan, Chile
    • Punta Arenas, Chile
    • Beagle Channel (Argentina/Chile)
    • Beagle Channel (Argentina/Chile)
    • Glacier Alley, Chile
    • Ushuaia, Argentina
    • Cape Horn, Chile
    • Port Stanley, Falkland Islands (Malvinas)
    • At Sea
    • At Sea
    • Montevideo, Uruguay
    • Buenos Aires, Argentina
    Returns – Buenos Aires, Argentina
    San Antonio, Chile - At Sea - Puerto Montt, Chile - Puerto Chacabuco, Chile - Chilean Fjords, Chile - Amalia Glacier, Chile - Strait of Magellan, Chile - Punta Arenas, Chile - Beagle Channel (Argentina/Chile) - Beagle Channel (Argentina/Chile) - Glacier Alley, Chile - Ushuaia, Argentina - Cape Horn, Chile - Port Stanley, Falkland Islands (Malvinas) - At Sea - At Sea - Montevideo, Uruguay - Buenos Aires, Argentina - Buenos Aires, Argentina
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • Book Now! $25 Deposit
    • Save on Sunshine! Save up to 50% plus Suite guests receive FREE Internet!
    • Limited Availability! Reduced Rates
    from
    $1,206* USD
    *restrictions apply
  • 15-Night South America Cruise

    15-Night South America Cruise
    Celebrity Cruises
    Celebrity Eclipse
    Depart: Sat, Dec 21, 2019
    Returns: Sun, Jan 5, 2020
    Depart – Buenos Aires, Argentina
    • Buenos Aires, Argentina
    • Montevideo, Uruguay
    • Punta del Este, Uruguay
    • At Sea
    • At Sea
    • Puerto Madryn, Argentina
    • At Sea
    • Cape Horn, Chile
    • Ushuaia, Argentina
    • Punta Arenas, Chile
    • Strait of Magellan, Chile
    • Chilean Fjords, Chile
    • Puerto Montt, Chile
    • At Sea
    Returns – San Antonio, Chile
    Buenos Aires, Argentina - Buenos Aires, Argentina - Montevideo, Uruguay - Punta del Este, Uruguay - At Sea - At Sea - Puerto Madryn, Argentina - At Sea - Cape Horn, Chile - Ushuaia, Argentina - Punta Arenas, Chile - Strait of Magellan, Chile - Chilean Fjords, Chile - Puerto Montt, Chile - At Sea - San Antonio, Chile
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • Sail Your Way Double Savings Offer! Save up to $1000 per stateroom!
    • Sail Plus! FREE Drinks & WiFi
    • Sail Plus! FREE Drinks & Tips
    • show more 
    from
    $1,199* USD
    *restrictions apply
    Gov't fees & taxes from: $297/pp.
  • 18-Night South America Cruise

    18-Night South America Cruise
    Princess Cruises
    Coral Princess
    Depart: Mon, Dec 2, 2019
    Returns: Fri, Dec 20, 2019
    Depart – Fort Lauderdale, Florida
    • At Sea
    • At Sea
    • Basseterre, St Kitts, Saint Kitts and Nevis
    • Fort-de-France, Martinique
    • At Sea
    • At Sea
    • At Sea
    • At Sea
    • At Sea
    • At Sea
    • Salvador, Brazil
    • At Sea
    • Rio de Janeiro, Brazil
    • Rio de Janeiro, Brazil
    • At Sea
    • At Sea
    • Montevideo, Uruguay
    Returns – Buenos Aires, Argentina
    Fort Lauderdale, Florida - At Sea - At Sea - Basseterre, St Kitts- Fort-de-France, Martinique - At Sea - At Sea - At Sea - At Sea - At Sea - At Sea - Salvador, Brazil - At Sea - Rio de Janeiro, Brazil - Rio de Janeiro, Brazil - At Sea - At Sea - Montevideo, Uruguay - Buenos Aires, Argentina
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • Non Refundable Deposit on select rates
    from
    $1,319* USD
    *restrictions apply
  • 8-Night South America Cruise

    8-Night South America Cruise
    Azamara
    Azamara Pursuit
    Depart: Sat, Nov 30, 2019
    Returns: Sun, Dec 8, 2019
    Depart – Rio de Janeiro, Brazil
    • Rio de Janeiro, Brazil
    • IlhaBela, Brazil
    • Santos, Brazil
    • At Sea
    • At Sea
    • Montevideo, Uruguay
    • Punta del Este, Uruguay
    Returns – Buenos Aires, Argentina
    Rio de Janeiro, Brazil - Rio de Janeiro, Brazil - IlhaBela, Brazil - Santos, Brazil - At Sea - At Sea - Montevideo, Uruguay - Punta del Este, Uruguay - Buenos Aires, Argentina
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • Sail Into Savings - up to 30% Off per person
    from
    $1,189* USD
    *restrictions apply
    Gov't fees & taxes from: $311/pp.
  • 21-Night South America Cruise

    BEST
    VALUE*
    21-Night South America Cruise
    Holland America Line
    ms Amsterdam
    Depart: Mon, Sep 23, 2019
    Returns: Mon, Oct 14, 2019
    Depart – Seattle, Washington
    • Vancouver, British Columbia
    • Victoria, British Columbia
    • At Sea
    • San Francisco, California
    • Monterey, California
    • Santa Barbara, California
    • San Diego, California
    • At Sea
    • Cabo San Lucas, Mexico
    • At Sea
    • At Sea
    • Huatulco, Mexico
    • At Sea
    • At Sea
    • Fuerte Amador, Panama
    • At Sea
    • Manta, Ecuador
    • At Sea
    • Salaverry, Peru
    • Callao, Peru
    Returns – Callao, Peru
    Seattle, Washington - Vancouver, British Columbia - Victoria, British Columbia - At Sea - San Francisco, California - Monterey, California - Santa Barbara, California - San Diego, California - At Sea - Cabo San Lucas, Mexico - At Sea - At Sea - Huatulco, Mexico - At Sea - At Sea - Fuerte Amador, Panama - At Sea - Manta, Ecuador - At Sea - Salaverry, Peru - Callao, Peru - Callao, Peru
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • FREE Beverage Package with select rates
    • Save on Sunshine! Save up to 50% plus Suite guests receive FREE Internet!
    from
    $1,543* USD
    *restrictions apply

Terms & Conditions

*Expedia Extras offers are per stateroom (unless otherwise stated) on select sailings, based on double occupancy, apply to new bookings only, are not combinable with any other offer, are capacity controlled and may be withdrawn without notice. Certain restrictions may apply. For full terms and conditions, click the specific Expedia Extra offer or contact your Expedia CruiseShipCenters Vacation Consultant.

Prices are per person (based on 2 passengers in the same stateroom), cruise only in USD dollars. Airfare, transfers, taxes, fees and port expenses are additional (unless otherwise stated). Prices vary by ship, stateroom type and sailing date. Prices and offers are subject to availability and change without notice, and are capacity controlled. Fuel supplement may apply. Expedia CruiseShipCenters is not responsible for errors that may occur due to the transfer of information from selected third parties, technical error, or human error.

Our default sort order is based on a number of relevant factors such as cruise line rating, ship rating, price per day, origin rating, destination rating, length of cruise, and booking window.

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At Expedia CruiseShipCenters, we are navigators of spectacular vacation experiences. As part of the number one brand in travel, this is our promise to you:


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George Leppla
Cruise & Vacation Consultant
Navigators Club - Emerald