877-781-7447 (SHIP)

Bob Eskridge
Cruise & Vacation Consultant

Cruise Advisory
Please be aware of any coronavirus (COVID-19) cruise advisories and review updates from the World Health Organization (WHO).
Cruise Advisory
Please be aware of any coronavirus (COVID-19) cruise advisories and review updates from the World Health Organization (WHO).
  • Destinations
    Panama Canal
  • Departure Ports
    Any Port
  • Departure Date Range
    Any Date
  • Adults (25+)
    2

292 Cruises

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Questions? 877-781-7447 (SHIP)

  • 9-Night Panama Canal Cruise

    up to
    $1000
    CREDIT*
    9-Night Panama Canal Cruise
    Norwegian Cruise Line
    Norwegian Sky
    Depart: Sat, Nov 20, 2021
    Returns: Mon, Nov 29, 2021
    Depart – Amador, Panama
    • Panama Canal
    • Puerto Limon, Costa Rica
    • At Sea
    • Kralendijk, Bonaire, Netherlands Antilles
    • Oranjestad, Aruba
    • Willemstad, Curacao, Netherlands Antilles
    • At Sea
    • Cartagena, Colombia
    Returns – Colon, Panama
    Amador, Panama - Panama Canal - Puerto Limon, Costa Rica - At Sea - Kralendijk, Bonaire- Oranjestad, Aruba - Willemstad, Curacao- At Sea - Cartagena, Colombia - Colon, Panama
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • Dash Sale! Up to $1000 Onboard Cash Credit - Ends 4/10
    • NCL 30% Off All Guests - Ends 3/31
    • FREE Drinks, Excursion Credit & WiFi
    • show more 
    from
    $1,042* USD
    *restrictions apply
    Gov't fees & taxes from: $377/pp.


  • 12-Night Panama Canal Cruise

    up to
    $1000
    CREDIT*
    12-Night Panama Canal Cruise
    Norwegian Cruise Line
    Norwegian Sun
    Depart: Mon, Feb 15, 2021
    Returns: Sat, Feb 27, 2021
    Depart – Port Canaveral, Florida
    • Great Stirrup Cay, Bahamas
    • At Sea
    • Ocho Rios, Jamaica
    • Georgetown, Grand Cayman, Cayman Islands
    • Cozumel, Mexico
    • Costa Maya, Mexico
    • Harvest Caye, Belize
    • Roatan, Honduras
    • At Sea
    • Puerto Limon, Costa Rica
    • Panama Canal
    Returns – Amador, Panama
    Port Canaveral, Florida - Great Stirrup Cay, Bahamas - At Sea - Ocho Rios, Jamaica - Georgetown, Grand Cayman- Cozumel, Mexico - Costa Maya, Mexico - Harvest Caye, Belize - Roatan, Honduras - At Sea - Puerto Limon, Costa Rica - Panama Canal - Amador, Panama
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • Dash Sale! Up to $1000 Onboard Cash Credit - Ends 4/10
    • NCL 30% Off All Guests - Ends 3/31
    • FREE Drinks, Excursion Credit & WiFi
    • show more 
    from
    $1,014* USD
    *restrictions apply
  • 14-Night Panama Canal Cruise

    up to
    $1000
    CREDIT*
    14-Night Panama Canal Cruise
    Norwegian Cruise Line
    Norwegian Sun
    Depart: Sun, Oct 18, 2020
    Returns: Sun, Nov 1, 2020
    Depart – San Diego, California
    • At Sea
    • Cabo San Lucas, Mexico
    • At Sea
    • At Sea
    • Puerto Quetzal, Guatemala
    • Puerto Corinto, Nicaragua
    • Puntarenas, Costa Rica
    • At Sea
    • Panama Canal
    • Cartagena, Colombia
    • Santa Marta, Colombia
    • At Sea
    • At Sea
    Returns – Port Canaveral, Florida
    San Diego, California - At Sea - Cabo San Lucas, Mexico - At Sea - At Sea - Puerto Quetzal, Guatemala - Puerto Corinto, Nicaragua - Puntarenas, Costa Rica - At Sea - Panama Canal - Cartagena, Colombia - Santa Marta, Colombia - At Sea - At Sea - Port Canaveral, Florida
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • Dash Sale! Up to $1000 Onboard Cash Credit - Ends 4/10
    • NCL 30% Off All Guests - Ends 3/31
    • FREE Drinks, Excursion Credit & WiFi
    • show more 
    from
    $1,029* USD
    *restrictions apply
  • 14-Night Panama Canal Cruise

    up to
    $50
    CREDIT*
    14-Night Panama Canal Cruise
    Carnival Cruise Lines
    Carnival Glory
    Depart: Sun, Nov 29, 2020
    Returns: Sun, Dec 13, 2020
    Depart – New Orleans, Louisiana
    • At Sea
    • At Sea
    • Montego Bay, Jamaica
    • At Sea
    • Oranjestad, Aruba
    • Kralendijk, Bonaire, Netherlands Antilles
    • At Sea
    • Cartagena, Colombia
    • Colon, Panama
    • Puerto Limon, Costa Rica
    • At Sea
    • Cozumel, Mexico
    • At Sea
    Returns – New Orleans, Louisiana
    New Orleans, Louisiana - At Sea - At Sea - Montego Bay, Jamaica - At Sea - Oranjestad, Aruba - Kralendijk, Bonaire- At Sea - Cartagena, Colombia - Colon, Panama - Puerto Limon, Costa Rica - At Sea - Cozumel, Mexico - At Sea - New Orleans, Louisiana
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • Early Saver + $50 Credit + Red Deposit - Ends 3/31
    • Early Saver Sale! Reduced Deposit - Ends 3/31
    • Great Rates
    from
    $719* USD
    *restrictions apply
    Gov't fees & taxes from: $143/pp.
  • 12-Night Panama Canal Cruise

    BEST
    VALUE*
    12-Night Panama Canal Cruise
    Celebrity Cruises
    Celebrity Constellation
    Depart: Wed, Dec 23, 2020
    Returns: Mon, Jan 4, 2021
    Depart – Tampa, Florida
    • At Sea
    • Cozumel, Mexico
    • At Sea
    • Puerto Limon, Costa Rica
    • Panama Canal
    • Colon, Panama
    • Cartagena, Colombia
    • Cartagena, Colombia
    • At Sea
    • Georgetown, Grand Cayman, Cayman Islands
    • At Sea
    Returns – Tampa, Florida
    Tampa, Florida - At Sea - Cozumel, Mexico - At Sea - Puerto Limon, Costa Rica - Panama Canal - Colon, Panama - Cartagena, Colombia - Cartagena, Colombia - At Sea - Georgetown, Grand Cayman- At Sea - Tampa, Florida
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • Sail Plus! Beverage Package & WiFi
    • Sail Plus! Beverage Package & Tips
    • Sail Plus! Beverage Package & $300 Credit
    • show more 
    from
    $2,069* USD
    *restrictions apply
  • 12-Night Panama Canal Cruise

    up to
    $50
    CREDIT*
    12-Night Panama Canal Cruise
    Carnival Cruise Lines
    Carnival Sunrise
    Depart: Mon, Oct 19, 2020
    Returns: Sat, Oct 31, 2020
    Depart – New York, New York
    • At Sea
    • At Sea
    • Grand Turk Island, Turks and Caicos Islands
    • At Sea
    • At Sea
    • Puerto Limon, Costa Rica
    • Panama Canal
    • Cartagena, Colombia
    • At Sea
    • Georgetown, Grand Cayman, Cayman Islands
    • At Sea
    Returns – Fort Lauderdale, Florida
    New York, New York - At Sea - At Sea - Grand Turk Island, Turks and Caicos Islands - At Sea - At Sea - Puerto Limon, Costa Rica - Panama Canal - Cartagena, Colombia - At Sea - Georgetown, Grand Cayman- At Sea - Fort Lauderdale, Florida
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • Early Saver + $50 Credit + Red Deposit - Ends 3/31
    • Early Saver Sale! Reduced Deposit - Ends 3/31
    • Great Rates
    from
    $549* USD
    *restrictions apply
    Gov't fees & taxes from: $412/pp.
  • 11-Night Panama Canal Cruise

    BEST
    VALUE*
    11-Night Panama Canal Cruise
    Celebrity Cruises
    Celebrity Edge
    Depart: Mon, Feb 14, 2022
    Returns: Fri, Feb 25, 2022
    Depart – Fort Lauderdale, Florida
    • At Sea
    • At Sea
    • Oranjestad, Aruba
    • Kralendijk, Bonaire, Netherlands Antilles
    • Willemstad, Curacao, Netherlands Antilles
    • At Sea
    • Panama Canal
    • Colon, Panama
    • Cartagena, Colombia
    • At Sea
    • At Sea
    Returns – Fort Lauderdale, Florida
    Fort Lauderdale, Florida - At Sea - At Sea - Oranjestad, Aruba - Kralendijk, Bonaire- Willemstad, Curacao- At Sea - Panama Canal - Colon, Panama - Cartagena, Colombia - At Sea - At Sea - Fort Lauderdale, Florida
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • Sail Plus! Beverage Package & WiFi
    • Sail Plus! Beverage Package & Tips
    • Sail Plus! Beverage Package & $300 Credit
    • show more 
    from
    $1,969* USD
    *restrictions apply
  • 10-Night Panama Canal Cruise

    up to
    $50
    CREDIT*
    10-Night Panama Canal Cruise
    Carnival Cruise Lines
    Carnival Fantasy
    Depart: Mon, Sep 14, 2020
    Returns: Thu, Sep 24, 2020
    Depart – Mobile, Alabama
    • At Sea
    • At Sea
    • At Sea
    • Panama Canal
    • Puerto Limon, Costa Rica
    • At Sea
    • Roatan, Honduras
    • Cozumel, Mexico
    • At Sea
    Returns – Mobile, Alabama
    Mobile, Alabama - At Sea - At Sea - At Sea - Panama Canal - Puerto Limon, Costa Rica - At Sea - Roatan, Honduras - Cozumel, Mexico - At Sea - Mobile, Alabama
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • Early Saver + $50 Credit + Red Deposit - Ends 3/31
    • Early Saver Sale! Reduced Deposit - Ends 3/31
    • Great Rates
    from
    $474* USD
    *restrictions apply
    Gov't fees & taxes from: $348/pp.
  • 11-Night Panama Canal Cruise

    up to
    $1000
    CREDIT*
    11-Night Panama Canal Cruise
    Norwegian Cruise Line
    Norwegian Pearl
    Depart: Mon, Nov 30, 2020
    Returns: Fri, Dec 11, 2020
    Depart – Miami, Florida
    • At Sea
    • At Sea
    • Cartagena, Colombia
    • Panama Canal
    • Colon, Panama
    • Puerto Limon, Costa Rica
    • At Sea
    • Roatan, Honduras
    • Harvest Caye, Belize
    • Costa Maya, Mexico
    • At Sea
    Returns – Miami, Florida
    Miami, Florida - At Sea - At Sea - Cartagena, Colombia - Panama Canal - Colon, Panama - Puerto Limon, Costa Rica - At Sea - Roatan, Honduras - Harvest Caye, Belize - Costa Maya, Mexico - At Sea - Miami, Florida
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • Dash Sale! Up to $1000 Onboard Cash Credit - Ends 4/10
    • NCL 30% Off All Guests - Ends 3/31
    • FREE Drinks, Excursion Credit & WiFi
    • show more 
    from
    $1,139* USD
    *restrictions apply
  • 11-Night Panama Canal Cruise

    up to
    $1000
    CREDIT*
    11-Night Panama Canal Cruise
    Norwegian Cruise Line
    Norwegian Pearl
    Depart: Wed, Nov 4, 2020
    Returns: Sun, Nov 15, 2020
    Depart – Miami, Florida
    • At Sea
    • At Sea
    • Cartagena, Colombia
    • Panama Canal
    • Colon, Panama
    • Puerto Limon, Costa Rica
    • At Sea
    • Roatan, Honduras
    • Harvest Caye, Belize
    • Costa Maya, Mexico
    • At Sea
    Returns – Miami, Florida
    Miami, Florida - At Sea - At Sea - Cartagena, Colombia - Panama Canal - Colon, Panama - Puerto Limon, Costa Rica - At Sea - Roatan, Honduras - Harvest Caye, Belize - Costa Maya, Mexico - At Sea - Miami, Florida
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • Dash Sale! Up to $1000 Onboard Cash Credit - Ends 4/10
    • NCL 30% Off All Guests - Ends 3/31
    • FREE Drinks, Excursion Credit & WiFi
    • show more 
    from
    $1,239* USD
    *restrictions apply

Terms & Conditions

*Expedia Extras offers are per stateroom (unless otherwise stated) on select sailings, based on double occupancy, apply to new bookings only, are not combinable with any other offer, are capacity controlled and may be withdrawn without notice. Certain restrictions may apply. For full terms and conditions, click the specific Expedia Extra offer or contact your Expedia CruiseShipCenters Vacation Consultant.

Prices are per person (based on 2 passengers in the same stateroom), cruise only in USD dollars. Airfare, transfers, taxes, fees and port expenses are additional (unless otherwise stated). Prices vary by ship, stateroom type and sailing date. Prices and offers are subject to availability and change without notice, and are capacity controlled. Fuel supplement may apply. Expedia CruiseShipCenters is not responsible for errors that may occur due to the transfer of information from selected third parties, technical error, or human error.

Our default sort order is based on a number of relevant factors such as cruise line rating, ship rating, price per day, origin rating, destination rating, length of cruise, and booking window.

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Bob Eskridge
Cruise & Vacation Consultant