877-855-2004

Adrienne Brown-Mallard
Cruise & Vacation Consultant

  • Destinations
    Panama Canal
  • Departure Ports
    Any Port
  • Departure Date Range
    Any Date
  • Adults (25+)
    2

359 Cruises

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  • 10-Night Panama Canal Cruise

    10-Night Panama Canal Cruise
    Princess Cruises
    Island Princess
    Depart: Sun, Oct 27, 2019
    Returns: Wed, Nov 6, 2019
    Depart – Fort Lauderdale, Florida
    • At Sea
    • Falmouth, Jamaica
    • At Sea
    • Cartagena, Colombia
    • Panama Canal
    • San Cristobal, Panama
    • Puerto Limon, Costa Rica
    • At Sea
    • Grand Cayman, Cayman Islands
    • At Sea
    Returns – Fort Lauderdale, Florida
    Fort Lauderdale, Florida - At Sea - Falmouth, Jamaica - At Sea - Cartagena, Colombia - Panama Canal - San Cristobal, Panama - Puerto Limon, Costa Rica - At Sea - Grand Cayman, Cayman Islands - At Sea - Fort Lauderdale, Florida
    from
    $819* USD
    *restrictions apply


  • 12-Night Panama Canal Cruise

    BEST
    VALUE*
    12-Night Panama Canal Cruise
    Norwegian Cruise Line
    Norwegian Pearl
    Depart: Fri, Nov 22, 2019
    Returns: Wed, Dec 4, 2019
    Depart – Miami, Florida
    • At Sea
    • At Sea
    • Cartagena, Colombia
    • Panama Canal
    • Colon, Panama
    • Puerto Limon, Costa Rica
    • At Sea
    • Roatan, Honduras
    • Harvest Caye, Belize
    • Costa Maya, Mexico
    • At Sea
    • Great Stirrup Cay, Bahamas
    Returns – Miami, Florida
    Miami, Florida - At Sea - At Sea - Cartagena, Colombia - Panama Canal - Colon, Panama - Puerto Limon, Costa Rica - At Sea - Roatan, Honduras - Harvest Caye, Belize - Costa Maya, Mexico - At Sea - Great Stirrup Cay, Bahamas - Miami, Florida
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • Take All Free! Open Bar, Dining, Excursions, WiFi - Ends 8/23
    • Excursion Credit, 3rd/4th FREE - Ends 8/23
    • 3rd and 4th Guest FREE - Ends 8/23
    • show more 
    from
    $579* USD
    *restrictions apply
    Gov't fees & taxes from: $466/pp.
  • 11-Night Panama Canal Cruise

    BEST
    VALUE*
    11-Night Panama Canal Cruise
    Norwegian Cruise Line
    Norwegian Pearl
    Depart: Mon, Dec 23, 2019
    Returns: Fri, Jan 3, 2020
    Depart – Miami, Florida
    • At Sea
    • At Sea
    • Cartagena, Colombia
    • Panama Canal
    • Colon, Panama
    • Puerto Limon, Costa Rica
    • At Sea
    • Harvest Caye, Belize
    • Roatan, Honduras
    • Costa Maya, Mexico
    • At Sea
    Returns – Miami, Florida
    Miami, Florida - At Sea - At Sea - Cartagena, Colombia - Panama Canal - Colon, Panama - Puerto Limon, Costa Rica - At Sea - Harvest Caye, Belize - Roatan, Honduras - Costa Maya, Mexico - At Sea - Miami, Florida
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • Take All Free! Open Bar, Dining, Excursions, WiFi - Ends 8/23
    • FREE WiFi & Excursion Credit - Ends 8/23
    • FREE WiFi Package - Ends 8/23
    • show more 
    from
    $1,249* USD
    *restrictions apply
    Gov't fees & taxes from: $420/pp.
  • 10-Night Panama Canal Cruise

    10-Night Panama Canal Cruise
    Holland America Line
    ms Zuiderdam
    Depart: Sun, Nov 10, 2019
    Returns: Wed, Nov 20, 2019
    Depart – Fort Lauderdale, Florida
    • Half Moon Cay, Bahamas
    • At Sea
    • Oranjestad, Aruba
    • Willemstad, Curacao, Netherlands Antilles
    • At Sea
    • Panama Canal
    • Gatun Lake, Panama
    • Panama Canal
    • Colon, Panama
    • Puerto Limon, Costa Rica
    • At Sea
    • At Sea
    Returns – Fort Lauderdale, Florida
    Fort Lauderdale, Florida - Half Moon Cay, Bahamas - At Sea - Oranjestad, Aruba - Willemstad, Curacao- At Sea - Panama Canal - Gatun Lake, Panama - Panama Canal - Colon, Panama - Puerto Limon, Costa Rica - At Sea - At Sea - Fort Lauderdale, Florida
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • Save on Sunshine! Save up to 50% plus Suite guests receive FREE Internet!
    from
    $575* USD
    *restrictions apply
  • 10-Night Panama Canal Cruise

    10-Night Panama Canal Cruise
    Princess Cruises
    Island Princess
    Depart: Sat, Nov 16, 2019
    Returns: Tue, Nov 26, 2019
    Depart – Fort Lauderdale, Florida
    • At Sea
    • Falmouth, Jamaica
    • At Sea
    • Cartagena, Colombia
    • Panama Canal
    • San Cristobal, Panama
    • Puerto Limon, Costa Rica
    • At Sea
    • Grand Cayman, Cayman Islands
    • At Sea
    Returns – Fort Lauderdale, Florida
    Fort Lauderdale, Florida - At Sea - Falmouth, Jamaica - At Sea - Cartagena, Colombia - Panama Canal - San Cristobal, Panama - Puerto Limon, Costa Rica - At Sea - Grand Cayman, Cayman Islands - At Sea - Fort Lauderdale, Florida
    from
    $719* USD
    *restrictions apply
  • 10-Night Panama Canal Cruise

    10-Night Panama Canal Cruise
    Princess Cruises
    Caribbean Princess
    Depart: Tue, Dec 10, 2019
    Returns: Fri, Dec 20, 2019
    Depart – Fort Lauderdale, Florida
    • At Sea
    • Grand Turk Island, Turks and Caicos Islands
    • At Sea
    • Cartagena, Colombia
    • Panama Canal
    • San Cristobal, Panama
    • Puerto Limon, Costa Rica
    • At Sea
    • Montego Bay, Jamaica
    • At Sea
    Returns – Fort Lauderdale, Florida
    Fort Lauderdale, Florida - At Sea - Grand Turk Island, Turks and Caicos Islands - At Sea - Cartagena, Colombia - Panama Canal - San Cristobal, Panama - Puerto Limon, Costa Rica - At Sea - Montego Bay, Jamaica - At Sea - Fort Lauderdale, Florida
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • Non Refundable Deposit on select rates
    from
    $679* USD
    *restrictions apply
  • 10-Night Panama Canal Cruise

    10-Night Panama Canal Cruise
    Princess Cruises
    Island Princess
    Depart: Fri, Dec 20, 2019
    Returns: Mon, Dec 30, 2019
    Depart – Fort Lauderdale, Florida
    • At Sea
    • Falmouth, Jamaica
    • At Sea
    • Cartagena, Colombia
    • Panama Canal
    • San Cristobal, Panama
    • Puerto Limon, Costa Rica
    • At Sea
    • Grand Cayman, Cayman Islands
    • At Sea
    Returns – Fort Lauderdale, Florida
    Fort Lauderdale, Florida - At Sea - Falmouth, Jamaica - At Sea - Cartagena, Colombia - Panama Canal - San Cristobal, Panama - Puerto Limon, Costa Rica - At Sea - Grand Cayman, Cayman Islands - At Sea - Fort Lauderdale, Florida
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • Non Refundable Deposit on select rates
    from
    $1,229* USD
    *restrictions apply
  • 15-Night Panama Canal Cruise

    15-Night Panama Canal Cruise
    Celebrity Cruises
    Celebrity Infinity
    Depart: Fri, Oct 25, 2019
    Returns: Sat, Nov 9, 2019
    Depart – Miami, Florida
    • At Sea
    • At Sea
    • Cartagena, Colombia
    • Colon, Panama
    • Panama Canal
    • At Sea
    • Puntarenas, Costa Rica
    • At Sea
    • Puerto Quetzal, Guatemala
    • At Sea
    • At Sea
    • Puerto Vallarta, Mexico
    • Cabo San Lucas, Mexico
    • At Sea
    Returns – San Diego, California
    Miami, Florida - At Sea - At Sea - Cartagena, Colombia - Colon, Panama - Panama Canal - At Sea - Puntarenas, Costa Rica - At Sea - Puerto Quetzal, Guatemala - At Sea - At Sea - Puerto Vallarta, Mexico - Cabo San Lucas, Mexico - At Sea - San Diego, California
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • Sail Your Way Savings Offer! Save up to $500 per stateroom!
    • Sail Plus! FREE Drinks & WiFi
    • Sail Plus! FREE Drinks & Tips
    • show more 
    from
    $1,199* USD
    *restrictions apply
    Gov't fees & taxes from: $342/pp.
  • 11-Night Panama Canal Cruise

    BEST
    VALUE*
    11-Night Panama Canal Cruise
    Norwegian Cruise Line
    Norwegian Pearl
    Depart: Mon, Nov 11, 2019
    Returns: Fri, Nov 22, 2019
    Depart – Miami, Florida
    • At Sea
    • At Sea
    • Cartagena, Colombia
    • Panama Canal
    • Colon, Panama
    • Puerto Limon, Costa Rica
    • At Sea
    • Harvest Caye, Belize
    • Roatan, Honduras
    • Costa Maya, Mexico
    • At Sea
    Returns – Miami, Florida
    Miami, Florida - At Sea - At Sea - Cartagena, Colombia - Panama Canal - Colon, Panama - Puerto Limon, Costa Rica - At Sea - Harvest Caye, Belize - Roatan, Honduras - Costa Maya, Mexico - At Sea - Miami, Florida
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • Take All Free! Open Bar, Dining, Excursions, WiFi - Ends 8/23
    • EXCLUSIVE - FREE Pre-Paid Gratuities! Ends 8/31
    • Excursion Credit, 3rd/4th FREE - Ends 8/23
    • show more 
    from
    $629* USD
    *restrictions apply
    Gov't fees & taxes from: $420/pp.
  • 11-Night Panama Canal Cruise

    11-Night Panama Canal Cruise
    Holland America Line
    ms Zuiderdam
    Depart: Wed, Apr 8, 2020
    Returns: Sun, Apr 19, 2020
    Depart – Fort Lauderdale, Florida
    • Half Moon Cay, Bahamas
    • At Sea
    • Oranjestad, Aruba
    • Willemstad, Curacao, Netherlands Antilles
    • At Sea
    • Cartagena, Colombia
    • Panama Canal
    • Gatun Lake, Panama
    • Panama Canal
    • Colon, Panama
    • Puerto Limon, Costa Rica
    • At Sea
    • At Sea
    Returns – Fort Lauderdale, Florida
    Fort Lauderdale, Florida - Half Moon Cay, Bahamas - At Sea - Oranjestad, Aruba - Willemstad, Curacao- At Sea - Cartagena, Colombia - Panama Canal - Gatun Lake, Panama - Panama Canal - Colon, Panama - Puerto Limon, Costa Rica - At Sea - At Sea - Fort Lauderdale, Florida
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • Save on Sunshine! Save up to 50% plus Suite guests receive FREE Internet!
    • Limited Availability! Reduced Rates
    from
    $890* USD
    *restrictions apply

Terms & Conditions

*Expedia Extras offers are per stateroom (unless otherwise stated) on select sailings, based on double occupancy, apply to new bookings only, are not combinable with any other offer, are capacity controlled and may be withdrawn without notice. Certain restrictions may apply. For full terms and conditions, click the specific Expedia Extra offer or contact your Expedia CruiseShipCenters Vacation Consultant.

Prices are per person (based on 2 passengers in the same stateroom), cruise only in USD dollars. Airfare, transfers, taxes, fees and port expenses are additional (unless otherwise stated). Prices vary by ship, stateroom type and sailing date. Prices and offers are subject to availability and change without notice, and are capacity controlled. Fuel supplement may apply. Expedia CruiseShipCenters is not responsible for errors that may occur due to the transfer of information from selected third parties, technical error, or human error.

Our default sort order is based on a number of relevant factors such as cruise line rating, ship rating, price per day, origin rating, destination rating, length of cruise, and booking window.

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Adrienne Brown-Mallard
Cruise & Vacation Consultant