1-844-556-6707 or 616-773-2727

Visit us at 5925 28th St. SE, Suite B
Grand Rapids, MI 49546

Have a Future Cruise Credit?
Our Vacation Consultants are here to help you secure an incredible deal and take the stress out of planning your next cruise. Find out more
Have a Future Cruise Credit?
Our Vacation Consultants are here to help you secure an incredible deal and take the stress out of planning your next cruise. Find out more
  • Destinations
    Panama Canal
  • Departure Ports
    Any Port
  • Departure Date Range
    Any Date
  • Adults (25+)
    2

249 Cruises

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Questions? 1-844-556-6707 or 616-773-2727

  • 8-Night Panama Canal Cruise

    up to
    $1000
    CREDIT*
    8-Night Panama Canal Cruise
    Norwegian Cruise Line
    Norwegian Sun
    Depart: Wed, Mar 17, 2021
    Returns: Thu, Mar 25, 2021
    Depart – Amador, Panama
    • Panama Canal
    • Puerto Limon, Costa Rica
    • At Sea
    • Oranjestad, Aruba
    • Kralendijk, Bonaire, Netherlands Antilles
    • Willemstad, Curacao, Netherlands Antilles
    • At Sea
    Returns – Colon, Panama
    Amador, Panama - Panama Canal - Puerto Limon, Costa Rica - At Sea - Oranjestad, Aruba - Kralendijk, Bonaire- Willemstad, Curacao- At Sea - Colon, Panama
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • Dash Sale! Up to $1000 Onboard Cash Credit - Ends 5/31
    • FREE Dining, Excursion Credit & WiFi
    • FREE Drinks, Dining, Excursion Credit & WiFi
    • show more 
    from
    $769* USD
    *restrictions apply
    Gov't fees & taxes from: $349/pp.


  • 10-Night Panama Canal Cruise

    10-Night Panama Canal Cruise
    Holland America Line
    ms Zuiderdam
    Depart: Sun, Nov 29, 2020
    Returns: Wed, Dec 9, 2020
    Depart – Fort Lauderdale, Florida
    • Half Moon Cay, Bahamas
    • At Sea
    • Willemstad, Curacao, Netherlands Antilles
    • Oranjestad, Aruba
    • At Sea
    • Panama Canal
    • Gatun Lake, Panama
    • Panama Canal
    • Colon, Panama
    • Puerto Limon, Costa Rica
    • At Sea
    • At Sea
    Returns – Fort Lauderdale, Florida
    Fort Lauderdale, Florida - Half Moon Cay, Bahamas - At Sea - Willemstad, Curacao- Oranjestad, Aruba - At Sea - Panama Canal - Gatun Lake, Panama - Panama Canal - Colon, Panama - Puerto Limon, Costa Rica - At Sea - At Sea - Fort Lauderdale, Florida
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • Limited Availability! Reduced Rates
    • $50 Onboard Cash Credit
    from
    $799* USD
    *restrictions apply
  • 11-Night Panama Canal Cruise

    up to
    $50
    CREDIT*
    11-Night Panama Canal Cruise
    Norwegian Cruise Line
    Norwegian Pearl
    Depart: Wed, Nov 4, 2020
    Returns: Sun, Nov 15, 2020
    Depart – Miami, Florida
    • At Sea
    • At Sea
    • Cartagena, Colombia
    • Panama Canal
    • Colon, Panama
    • Puerto Limon, Costa Rica
    • At Sea
    • Roatan, Honduras
    • Harvest Caye, Belize
    • Costa Maya, Mexico
    • At Sea
    Returns – Miami, Florida
    Miami, Florida - At Sea - At Sea - Cartagena, Colombia - Panama Canal - Colon, Panama - Puerto Limon, Costa Rica - At Sea - Roatan, Honduras - Harvest Caye, Belize - Costa Maya, Mexico - At Sea - Miami, Florida
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • FREE Dining, Excursion Credit & WiFi
    • FREE Drinks, Dining, Excursion Credit & WiFi
    • FREE Drinks, Excursion Credit & WiFi
    • show more 
    from
    $749* USD
    *restrictions apply
    Gov't fees & taxes from: $467/pp.
  • 11-Night Panama Canal Cruise

    up to
    $50
    CREDIT*
    11-Night Panama Canal Cruise
    Norwegian Cruise Line
    Norwegian Pearl
    Depart: Mon, Nov 30, 2020
    Returns: Fri, Dec 11, 2020
    Depart – Miami, Florida
    • At Sea
    • At Sea
    • Cartagena, Colombia
    • Panama Canal
    • Colon, Panama
    • Puerto Limon, Costa Rica
    • At Sea
    • Roatan, Honduras
    • Harvest Caye, Belize
    • Costa Maya, Mexico
    • At Sea
    Returns – Miami, Florida
    Miami, Florida - At Sea - At Sea - Cartagena, Colombia - Panama Canal - Colon, Panama - Puerto Limon, Costa Rica - At Sea - Roatan, Honduras - Harvest Caye, Belize - Costa Maya, Mexico - At Sea - Miami, Florida
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • FREE Dining, Excursion Credit & WiFi
    • FREE Drinks, Dining, Excursion Credit & WiFi
    • FREE Drinks, Excursion Credit & WiFi
    • show more 
    from
    $749* USD
    *restrictions apply
    Gov't fees & taxes from: $467/pp.
  • 9-Night Panama Canal Cruise

    up to
    $1000
    CREDIT*
    9-Night Panama Canal Cruise
    Norwegian Cruise Line
    Norwegian Sky
    Depart: Thu, Nov 11, 2021
    Returns: Sat, Nov 20, 2021
    Depart – Colon, Panama
    • Cartagena, Colombia
    • At Sea
    • Kralendijk, Bonaire, Netherlands Antilles
    • Oranjestad, Aruba
    • Willemstad, Curacao, Netherlands Antilles
    • At Sea
    • Puerto Limon, Costa Rica
    • Panama Canal
    Returns – Amador, Panama
    Colon, Panama - Cartagena, Colombia - At Sea - Kralendijk, Bonaire- Oranjestad, Aruba - Willemstad, Curacao- At Sea - Puerto Limon, Costa Rica - Panama Canal - Amador, Panama
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • Dash Sale! Up to $1000 Onboard Cash Credit - Ends 5/31
    • FREE Dining, Excursion Credit & WiFi
    • FREE Drinks, Dining, Excursion Credit & WiFi
    • show more 
    from
    $849* USD
    *restrictions apply
    Gov't fees & taxes from: $371/pp.
  • 17-Night Panama Canal Cruise

    17-Night Panama Canal Cruise
    Holland America Line
    ms Zaandam
    Depart: Sat, Oct 31, 2020
    Returns: Tue, Nov 17, 2020
    Depart – Fort Lauderdale, Florida
    • At Sea
    • At Sea
    • Oranjestad, Aruba
    • At Sea
    • Panama Canal
    • Fuerte Amador, Panama
    • Fuerte Amador, Panama
    • At Sea
    • Caldera, Costa Rica
    • Puerto Corinto, Nicaragua
    • Puerto Quetzal, Guatemala
    • Puerto Chiapas, Mexico
    • Huatulco, Mexico
    • At Sea
    • Puerto Vallarta, Mexico
    • At Sea
    • At Sea
    Returns – San Diego, California
    Fort Lauderdale, Florida - At Sea - At Sea - Oranjestad, Aruba - At Sea - Panama Canal - Fuerte Amador, Panama - Fuerte Amador, Panama - At Sea - Caldera, Costa Rica - Puerto Corinto, Nicaragua - Puerto Quetzal, Guatemala - Puerto Chiapas, Mexico - Huatulco, Mexico - At Sea - Puerto Vallarta, Mexico - At Sea - At Sea - San Diego, California
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • Limited Availability! Reduced Rates
    from
    $1,449* USD
    *restrictions apply
  • 11-Night Panama Canal Cruise

    11-Night Panama Canal Cruise
    Holland America Line
    ms Zuiderdam
    Depart: Wed, Dec 9, 2020
    Returns: Sun, Dec 20, 2020
    Depart – Fort Lauderdale, Florida
    • Half Moon Cay, Bahamas
    • At Sea
    • Oranjestad, Aruba
    • Willemstad, Curacao, Netherlands Antilles
    • At Sea
    • Cartagena, Colombia
    • Panama Canal
    • Gatun Lake, Panama
    • Panama Canal
    • Colon, Panama
    • Puerto Limon, Costa Rica
    • At Sea
    • At Sea
    Returns – Fort Lauderdale, Florida
    Fort Lauderdale, Florida - Half Moon Cay, Bahamas - At Sea - Oranjestad, Aruba - Willemstad, Curacao- At Sea - Cartagena, Colombia - Panama Canal - Gatun Lake, Panama - Panama Canal - Colon, Panama - Puerto Limon, Costa Rica - At Sea - At Sea - Fort Lauderdale, Florida
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • Limited Availability! Reduced Rates
    from
    $899* USD
    *restrictions apply
  • 14-Night Panama Canal Cruise

    BEST
    VALUE*
    14-Night Panama Canal Cruise
    Oceania Cruises
    Marina
    Depart: Sat, Dec 5, 2020
    Returns: Sat, Dec 19, 2020
    Depart – Miami, Florida
    • Old Bahama Channel
    • Caribbean Sea
    • Oranjestad, Aruba
    • Willemstad, Netherlands
    • Santa Marta, Colombia
    • Cartagena, Colombia
    • Panama Canal
    • Fuerte Amador, Panama
    • Fuerte Amador, Panama
    • Pacific Ocean
    • Manta, Ecuador
    • Pacific Ocean
    • Salaverry, Peru
    • Lima, Peru
    Returns – Lima, Peru
    Miami, Florida - Old Bahama Channel - Caribbean Sea - Oranjestad, Aruba - Willemstad, Netherlands - Santa Marta, Colombia - Cartagena, Colombia - Panama Canal - Fuerte Amador, Panama - Fuerte Amador, Panama - Pacific Ocean - Manta, Ecuador - Pacific Ocean - Salaverry, Peru - Lima, Peru - Lima, Peru
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • The Ultimate Sale - Enjoy up to 50% Savings!
    • OLife CHOICE! Includes Air and Unlimited Internet PLUS your choice of FREE Excursions, Beverage Package, or Onboard Cash Credit on select sailings, and rates
    from
    $2,599* USD
    *restrictions apply
  • 10-Night Panama Canal Cruise

    BEST
    VALUE*
    10-Night Panama Canal Cruise
    Princess Cruises
    Crown Princess
    Depart: Tue, Dec 29, 2020
    Returns: Fri, Jan 8, 2021
    Depart – Fort Lauderdale, Florida
    • At Sea
    • Falmouth, Jamaica
    • At Sea
    • Cartagena, Colombia
    • Panama Canal
    • San Cristobal, Panama
    • Puerto Limon, Costa Rica
    • At Sea
    • Grand Cayman, Cayman Islands
    • At Sea
    Returns – Fort Lauderdale, Florida
    Fort Lauderdale, Florida - At Sea - Falmouth, Jamaica - At Sea - Cartagena, Colombia - Panama Canal - San Cristobal, Panama - Puerto Limon, Costa Rica - At Sea - Grand Cayman, Cayman Islands - At Sea - Fort Lauderdale, Florida
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • Princess Plus - FREE Drinks, Gratuities & Wi-Fi on select rates!
    • Non Refundable Deposit on select rates
    from
    $849* USD
    *restrictions apply
  • 10-Night Panama Canal Cruise

    BEST
    VALUE*
    10-Night Panama Canal Cruise
    Princess Cruises
    Crown Princess
    Depart: Sat, Dec 19, 2020
    Returns: Tue, Dec 29, 2020
    Depart – Fort Lauderdale, Florida
    • At Sea
    • Falmouth, Jamaica
    • At Sea
    • Cartagena, Colombia
    • Panama Canal
    • San Cristobal, Panama
    • Puerto Limon, Costa Rica
    • At Sea
    • Grand Cayman, Cayman Islands
    • At Sea
    Returns – Fort Lauderdale, Florida
    Fort Lauderdale, Florida - At Sea - Falmouth, Jamaica - At Sea - Cartagena, Colombia - Panama Canal - San Cristobal, Panama - Puerto Limon, Costa Rica - At Sea - Grand Cayman, Cayman Islands - At Sea - Fort Lauderdale, Florida
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • Princess Plus - FREE Drinks, Gratuities & Wi-Fi on select rates!
    • Receive a $60 Onboard Cash Credit per stateroom
    • Non Refundable Deposit on select rates
    from
    $849* USD
    *restrictions apply

Terms & Conditions

*Expedia Extras offers are per stateroom (unless otherwise stated) on select sailings, based on double occupancy, apply to new bookings only, are not combinable with any other offer, are capacity controlled and may be withdrawn without notice. Certain restrictions may apply. For full terms and conditions, click the specific Expedia Extra offer or contact your Expedia CruiseShipCenters Vacation Consultant.

Prices are per person (based on 2 passengers in the same stateroom), cruise only in USD dollars. Airfare, transfers, taxes, fees and port expenses are additional (unless otherwise stated). Prices vary by ship, stateroom type and sailing date. Prices and offers are subject to availability and change without notice, and are capacity controlled. Fuel supplement may apply. Expedia CruiseShipCenters is not responsible for errors that may occur due to the transfer of information from selected third parties, technical error, or human error.

Our default sort order is based on a number of relevant factors such as cruise line rating, ship rating, price per day, origin rating, destination rating, length of cruise, and booking window.

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At Expedia CruiseShipCenters, we are navigators of spectacular vacation experiences. As part of the number one brand in travel, this is our promise to you:


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Monday 9:30am - 6:00pm
Tuesday 9:30am - 6:00pm
Wednesday 9:30am - 6:00pm
Thursday 9:30am - 6:00pm
Friday 9:30am - 6:00pm
Saturday 10:00am - 2:00pm
Sunday Closed