850-604-0233

Visit us at 4424 Commons Drive East Suite B-2
Destin, FL 32541

  • Destinations
    Panama Canal
  • Departure Ports
    Any Port
  • Departure Date Range
    Any Date
  • Adults (25+)
    2

323 Cruises

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Questions? 850-604-0233

  • 10-Night Panama Canal Cruise

    10-Night Panama Canal Cruise
    Princess Cruises
    Caribbean Princess
    Depart: Tue, Dec 10, 2019
    Returns: Fri, Dec 20, 2019
    Depart – Fort Lauderdale, Florida
    • At Sea
    • Grand Turk Island, Turks and Caicos Islands
    • At Sea
    • Cartagena, Colombia
    • Panama Canal
    • San Cristobal, Panama
    • Puerto Limon, Costa Rica
    • At Sea
    • Montego Bay, Jamaica
    • At Sea
    Returns – Fort Lauderdale, Florida
    Fort Lauderdale, Florida - At Sea - Grand Turk Island, Turks and Caicos Islands - At Sea - Cartagena, Colombia - Panama Canal - San Cristobal, Panama - Puerto Limon, Costa Rica - At Sea - Montego Bay, Jamaica - At Sea - Fort Lauderdale, Florida
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • Exclusive Awesome Alaska Sale - Coupon Books and Reduced Deposit!
    from
    $529* USD
    *restrictions apply


  • 10-Night Panama Canal Cruise

    10-Night Panama Canal Cruise
    Princess Cruises
    Island Princess
    Depart: Tue, Nov 26, 2019
    Returns: Fri, Dec 6, 2019
    Depart – Fort Lauderdale, Florida
    • At Sea
    • Grand Cayman, Cayman Islands
    • At Sea
    • Cartagena, Colombia
    • Panama Canal
    • San Cristobal, Panama
    • Puerto Limon, Costa Rica
    • At Sea
    • Montego Bay, Jamaica
    • At Sea
    Returns – Fort Lauderdale, Florida
    Fort Lauderdale, Florida - At Sea - Grand Cayman, Cayman Islands - At Sea - Cartagena, Colombia - Panama Canal - San Cristobal, Panama - Puerto Limon, Costa Rica - At Sea - Montego Bay, Jamaica - At Sea - Fort Lauderdale, Florida
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • Exclusive Awesome Alaska Sale - Coupon Books and Reduced Deposit!
    from
    $599* USD
    *restrictions apply
  • 11-Night Panama Canal Cruise

    BEST
    VALUE*
    11-Night Panama Canal Cruise
    Norwegian Cruise Line
    Norwegian Pearl
    Depart: Sun, Apr 19, 2020
    Returns: Thu, Apr 30, 2020
    Depart – Miami, Florida
    • At Sea
    • At Sea
    • Cartagena, Colombia
    • Panama Canal
    • Colon, Panama
    • Puerto Limon, Costa Rica
    • At Sea
    • Roatan, Honduras
    • Harvest Caye, Belize
    • Costa Maya, Mexico
    • At Sea
    Returns – Miami, Florida
    Miami, Florida - At Sea - At Sea - Cartagena, Colombia - Panama Canal - Colon, Panama - Puerto Limon, Costa Rica - At Sea - Roatan, Honduras - Harvest Caye, Belize - Costa Maya, Mexico - At Sea - Miami, Florida
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • Take All Free! Open Bar, Dining, Excursions, WiFi - Ends 11/22
    • FREE Drinks & 3rd/4th FREE - Ends 11/22
    • FREE Drinks & Excursion - Ends 11/22
    • show more 
    from
    $699* USD
    *restrictions apply
  • 14-Night Panama Canal Cruise

    14-Night Panama Canal Cruise
    Carnival Cruise Lines
    Carnival Glory
    Depart: Sun, Feb 9, 2020
    Returns: Sun, Feb 23, 2020
    Depart – New Orleans, Louisiana
    • At Sea
    • At Sea
    • Montego Bay, Jamaica
    • At Sea
    • Oranjestad, Aruba
    • Kralendijk, Bonaire, Netherlands Antilles
    • At Sea
    • Cartagena, Colombia
    • Panama Canal
    • Puerto Limon, Costa Rica
    • At Sea
    • Cozumel, Mexico
    • At Sea
    Returns – New Orleans, Louisiana
    New Orleans, Louisiana - At Sea - At Sea - Montego Bay, Jamaica - At Sea - Oranjestad, Aruba - Kralendijk, Bonaire- At Sea - Cartagena, Colombia - Panama Canal - Puerto Limon, Costa Rica - At Sea - Cozumel, Mexico - At Sea - New Orleans, Louisiana
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • FREE Cabin Upgrade! Ends 11/19
    from
    $1,098* USD
    *restrictions apply
    Gov't fees & taxes from: $333/pp.
  • 10-Night Panama Canal Cruise

    10-Night Panama Canal Cruise
    Princess Cruises
    Island Princess
    Depart: Tue, Mar 17, 2020
    Returns: Fri, Mar 27, 2020
    Depart – Fort Lauderdale, Florida
    • At Sea
    • Grand Turk Island, Turks and Caicos Islands
    • At Sea
    • Cartagena, Colombia
    • Panama Canal
    • San Cristobal, Panama
    • Puerto Limon, Costa Rica
    • At Sea
    • Ocho Rios, Jamaica
    • At Sea
    Returns – Fort Lauderdale, Florida
    Fort Lauderdale, Florida - At Sea - Grand Turk Island, Turks and Caicos Islands - At Sea - Cartagena, Colombia - Panama Canal - San Cristobal, Panama - Puerto Limon, Costa Rica - At Sea - Ocho Rios, Jamaica - At Sea - Fort Lauderdale, Florida
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • End of Year Sale - Limited Time Savings and Reduced Deposit
    • Exclusive Awesome Alaska Sale - Coupon Books and Reduced Deposit!
    • Non Refundable Deposit on select rates
    from
    $819* USD
    *restrictions apply
  • 11-Night Panama Canal Cruise

    up to
    $50
    CREDIT*
    11-Night Panama Canal Cruise
    Norwegian Cruise Line
    Norwegian Pearl
    Depart: Wed, Apr 8, 2020
    Returns: Sun, Apr 19, 2020
    Depart – Miami, Florida
    • At Sea
    • At Sea
    • Willemstad, Curacao, Netherlands Antilles
    • Oranjestad, Aruba
    • Santa Marta, Colombia
    • Cartagena, Colombia
    • Panama Canal
    • Colon, Panama
    • At Sea
    • Georgetown, Grand Cayman, Cayman Islands
    • At Sea
    Returns – Miami, Florida
    Miami, Florida - At Sea - At Sea - Willemstad, Curacao- Oranjestad, Aruba - Santa Marta, Colombia - Cartagena, Colombia - Panama Canal - Colon, Panama - At Sea - Georgetown, Grand Cayman- At Sea - Miami, Florida
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • FREE Drinks, Dining, Excursion Credit & WiFi - Ends 11/22
    • FREE Drinks & Excursion - Ends 11/22
    • FREE WiFi & Excursion Credit - Ends 11/22
    • show more 
    from
    $829* USD
    *restrictions apply
  • 14-Night Panama Canal Cruise

    14-Night Panama Canal Cruise
    Norwegian Cruise Line
    Norwegian Dawn
    Depart: Sun, Dec 1, 2019
    Returns: Sun, Dec 15, 2019
    Depart – Tampa, Florida
    • Key West, Florida
    • At Sea
    • Falmouth, Jamaica
    • At Sea
    • Santa Marta, Colombia
    • Cartagena, Colombia
    • Panama Canal
    • Colon, Panama
    • Puerto Limon, Costa Rica
    • At Sea
    • Roatan, Honduras
    • Harvest Caye, Belize
    • Costa Maya, Mexico
    • At Sea
    Returns – Tampa, Florida
    Tampa, Florida - Key West, Florida - At Sea - Falmouth, Jamaica - At Sea - Santa Marta, Colombia - Cartagena, Colombia - Panama Canal - Colon, Panama - Puerto Limon, Costa Rica - At Sea - Roatan, Honduras - Harvest Caye, Belize - Costa Maya, Mexico - At Sea - Tampa, Florida
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • FREE Drinks, WiFi & Excursion Credit SUITE - Ends 11/22
    • FREE Drinks, Dining, Excursion Credit & WiFi - Ends 11/22
    • FREE WiFi & Excursion Credit - Ends 11/22
    • show more 
    from
    $1,899* USD
    *restrictions apply
    Gov't fees & taxes from: $460/pp.
  • 10-Night Panama Canal Cruise

    10-Night Panama Canal Cruise
    Princess Cruises
    Caribbean Princess
    Depart: Wed, Nov 20, 2019
    Returns: Sat, Nov 30, 2019
    Depart – Fort Lauderdale, Florida
    • At Sea
    • Grand Cayman, Cayman Islands
    • At Sea
    • Cartagena, Colombia
    • Panama Canal
    • San Cristobal, Panama
    • Puerto Limon, Costa Rica
    • At Sea
    • Falmouth, Jamaica
    • At Sea
    Returns – Fort Lauderdale, Florida
    Fort Lauderdale, Florida - At Sea - Grand Cayman, Cayman Islands - At Sea - Cartagena, Colombia - Panama Canal - San Cristobal, Panama - Puerto Limon, Costa Rica - At Sea - Falmouth, Jamaica - At Sea - Fort Lauderdale, Florida
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • Exclusive Awesome Alaska Sale - Coupon Books and Reduced Deposit!
    from
    $569* USD
    *restrictions apply
  • 10-Night Panama Canal Cruise

    10-Night Panama Canal Cruise
    Princess Cruises
    Caribbean Princess
    Depart: Sat, Nov 30, 2019
    Returns: Tue, Dec 10, 2019
    Depart – Fort Lauderdale, Florida
    • At Sea
    • Falmouth, Jamaica
    • At Sea
    • Cartagena, Colombia
    • Panama Canal
    • San Cristobal, Panama
    • Puerto Limon, Costa Rica
    • At Sea
    • Grand Cayman, Cayman Islands
    • At Sea
    Returns – Fort Lauderdale, Florida
    Fort Lauderdale, Florida - At Sea - Falmouth, Jamaica - At Sea - Cartagena, Colombia - Panama Canal - San Cristobal, Panama - Puerto Limon, Costa Rica - At Sea - Grand Cayman, Cayman Islands - At Sea - Fort Lauderdale, Florida
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • Exclusive Awesome Alaska Sale - Coupon Books and Reduced Deposit!
    from
    $549* USD
    *restrictions apply
  • 16-Night Panama Canal Cruise

    BEST
    VALUE*
    16-Night Panama Canal Cruise
    Norwegian Cruise Line
    Norwegian Bliss
    Depart: Fri, Nov 6, 2020
    Returns: Sun, Nov 22, 2020
    Depart – Los Angeles, California
    • At Sea
    • Cabo San Lucas, Mexico
    • Puerto Vallarta, Mexico
    • At Sea
    • At Sea
    • Puerto Quetzal, Guatemala
    • At Sea
    • Caldera, Costa Rica
    • At Sea
    • Panama Canal
    • Cartagena, Colombia
    • Santa Marta, Colombia
    • Oranjestad, Aruba
    • At Sea
    • At Sea
    Returns – Miami, Florida
    Los Angeles, California - At Sea - Cabo San Lucas, Mexico - Puerto Vallarta, Mexico - At Sea - At Sea - Puerto Quetzal, Guatemala - At Sea - Caldera, Costa Rica - At Sea - Panama Canal - Cartagena, Colombia - Santa Marta, Colombia - Oranjestad, Aruba - At Sea - At Sea - Miami, Florida
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • Take All Free! Open Bar, Dining, Excursions, WiFi - Ends 11/22
    • FREE Drinks, WiFi & Excursion Credit SUITE - Ends 11/22
    • FREE Drinks, Dining, Excursion Credit & WiFi - Ends 11/22
    • show more 
    from
    $1,329* USD
    *restrictions apply

Terms & Conditions

*Expedia Extras offers are per stateroom (unless otherwise stated) on select sailings, based on double occupancy, apply to new bookings only, are not combinable with any other offer, are capacity controlled and may be withdrawn without notice. Certain restrictions may apply. For full terms and conditions, click the specific Expedia Extra offer or contact your Expedia CruiseShipCenters Vacation Consultant.

Prices are per person (based on 2 passengers in the same stateroom), cruise only in USD dollars. Airfare, transfers, taxes, fees and port expenses are additional (unless otherwise stated). Prices vary by ship, stateroom type and sailing date. Prices and offers are subject to availability and change without notice, and are capacity controlled. Fuel supplement may apply. Expedia CruiseShipCenters is not responsible for errors that may occur due to the transfer of information from selected third parties, technical error, or human error.

Our default sort order is based on a number of relevant factors such as cruise line rating, ship rating, price per day, origin rating, destination rating, length of cruise, and booking window.

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