1-800-745-4015

Visit us at 24321 Avenida de la Carlota
Laguna Hills, CA 92653
Suite H-3

Have a Future Cruise Credit?
Our Vacation Consultants are here to help you secure an incredible deal and take the stress out of planning your next cruise. Find out more
Have a Future Cruise Credit?
Our Vacation Consultants are here to help you secure an incredible deal and take the stress out of planning your next cruise. Find out more
  • Destinations
    Panama Canal
  • Departure Ports
    Any Port
  • Departure Date Range
    Any Date
  • Adults (25+)
    2

273 Cruises

Show Search Filters
Loading
from
to

Questions? 1-800-745-4015

  • 8-Night Panama Canal Cruise

    up to
    $1000
    CREDIT*
    8-Night Panama Canal Cruise
    Norwegian Cruise Line
    Norwegian Sun
    Depart: Wed, Mar 17, 2021
    Returns: Thu, Mar 25, 2021
    Depart – Amador, Panama
    • Panama Canal
    • Puerto Limon, Costa Rica
    • At Sea
    • Oranjestad, Aruba
    • Kralendijk, Bonaire, Netherlands Antilles
    • Willemstad, Curacao, Netherlands Antilles
    • At Sea
    Returns – Colon, Panama
    Amador, Panama - Panama Canal - Puerto Limon, Costa Rica - At Sea - Oranjestad, Aruba - Kralendijk, Bonaire- Willemstad, Curacao- At Sea - Colon, Panama
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • Dash Sale! Up to $1000 Onboard Cash Credit - Ends 5/31
    • FREE Dining, Excursion Credit & WiFi
    • FREE Drinks, Dining, Excursion Credit & WiFi
    • show more 
    from
    $769* USD
    *restrictions apply
    Gov't fees & taxes from: $349/pp.


  • 9-Night Panama Canal Cruise

    up to
    $50
    CREDIT*
    9-Night Panama Canal Cruise
    Carnival Cruise Lines
    Carnival Radiance
    Depart: Fri, Nov 26, 2021
    Returns: Sun, Dec 5, 2021
    Depart – Galveston, Texas
    • At Sea
    • Cozumel, Mexico
    • At Sea
    • Puerto Limon, Costa Rica
    • Panama Canal
    • At Sea
    • At Sea
    • At Sea
    Returns – Galveston, Texas
    Galveston, Texas - At Sea - Cozumel, Mexico - At Sea - Puerto Limon, Costa Rica - Panama Canal - At Sea - At Sea - At Sea - Galveston, Texas
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • Exlusive Reduced Deposit & $50 Credit- Ends 6/1
    • Early Saver Sale! Reduced Deposit - Ends 6/1
    • Great Rates
    from
    $649* USD
    *restrictions apply
    Gov't fees & taxes from: $308/pp.
  • 17-Night Panama Canal Cruise

    up to
    $50
    CREDIT*
    17-Night Panama Canal Cruise
    Carnival Cruise Lines
    Carnival Freedom
    Depart: Sat, Apr 10, 2021
    Returns: Tue, Apr 27, 2021
    Depart – Galveston, Texas
    • At Sea
    • At Sea
    • At Sea
    • Santa Marta, Colombia
    • Cartagena, Colombia
    • Panama Canal
    • At Sea
    • Puntarenas, Costa Rica
    • At Sea
    • At Sea
    • At Sea
    • Cabo San Lucas, Mexico
    • At Sea
    • At Sea
    • At Sea
    • At Sea
    Returns – Seattle, Washington
    Galveston, Texas - At Sea - At Sea - At Sea - Santa Marta, Colombia - Cartagena, Colombia - Panama Canal - At Sea - Puntarenas, Costa Rica - At Sea - At Sea - At Sea - Cabo San Lucas, Mexico - At Sea - At Sea - At Sea - At Sea - Seattle, Washington
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • Exlusive Reduced Deposit & $50 Credit- Ends 6/1
    • Early Saver Sale! Reduced Deposit - Ends 6/1
    • Great Rates
    from
    $1,029* USD
    *restrictions apply
    Gov't fees & taxes from: $395/pp.
  • 8-Night Panama Canal Cruise

    up to
    $50
    CREDIT*
    8-Night Panama Canal Cruise
    Carnival Cruise Lines
    Carnival Legend
    Depart: Sat, Mar 6, 2021
    Returns: Sun, Mar 14, 2021
    Depart – Tampa, Florida
    • At Sea
    • At Sea
    • Puerto Limon, Costa Rica
    • Panama Canal
    • At Sea
    • Georgetown, Grand Cayman, Cayman Islands
    • At Sea
    Returns – Tampa, Florida
    Tampa, Florida - At Sea - At Sea - Puerto Limon, Costa Rica - Panama Canal - At Sea - Georgetown, Grand Cayman- At Sea - Tampa, Florida
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • Exlusive Reduced Deposit & $50 Credit- Ends 6/1
    • Early Saver Sale! Reduced Deposit - Ends 6/1
    • Great Rates
    from
    $759* USD
    *restrictions apply
    Gov't fees & taxes from: $345/pp.
  • 11-Night Panama Canal Cruise

    up to
    $50
    CREDIT*
    11-Night Panama Canal Cruise
    Norwegian Cruise Line
    Norwegian Pearl
    Depart: Wed, Nov 4, 2020
    Returns: Sun, Nov 15, 2020
    Depart – Miami, Florida
    • At Sea
    • At Sea
    • Cartagena, Colombia
    • Panama Canal
    • Colon, Panama
    • Puerto Limon, Costa Rica
    • At Sea
    • Roatan, Honduras
    • Harvest Caye, Belize
    • Costa Maya, Mexico
    • At Sea
    Returns – Miami, Florida
    Miami, Florida - At Sea - At Sea - Cartagena, Colombia - Panama Canal - Colon, Panama - Puerto Limon, Costa Rica - At Sea - Roatan, Honduras - Harvest Caye, Belize - Costa Maya, Mexico - At Sea - Miami, Florida
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • FREE Dining, Excursion Credit & WiFi
    • FREE Drinks, Dining, Excursion Credit & WiFi
    • FREE Drinks, Excursion Credit & WiFi
    • show more 
    from
    $749* USD
    *restrictions apply
    Gov't fees & taxes from: $467/pp.
  • 11-Night Panama Canal Cruise

    up to
    $50
    CREDIT*
    11-Night Panama Canal Cruise
    Norwegian Cruise Line
    Norwegian Pearl
    Depart: Mon, Nov 30, 2020
    Returns: Fri, Dec 11, 2020
    Depart – Miami, Florida
    • At Sea
    • At Sea
    • Cartagena, Colombia
    • Panama Canal
    • Colon, Panama
    • Puerto Limon, Costa Rica
    • At Sea
    • Roatan, Honduras
    • Harvest Caye, Belize
    • Costa Maya, Mexico
    • At Sea
    Returns – Miami, Florida
    Miami, Florida - At Sea - At Sea - Cartagena, Colombia - Panama Canal - Colon, Panama - Puerto Limon, Costa Rica - At Sea - Roatan, Honduras - Harvest Caye, Belize - Costa Maya, Mexico - At Sea - Miami, Florida
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • FREE Dining, Excursion Credit & WiFi
    • FREE Drinks, Dining, Excursion Credit & WiFi
    • FREE Drinks, Excursion Credit & WiFi
    • show more 
    from
    $749* USD
    *restrictions apply
    Gov't fees & taxes from: $467/pp.
  • 11-Night Panama Canal Cruise

    up to
    $1000
    CREDIT*
    11-Night Panama Canal Cruise
    Norwegian Cruise Line
    Norwegian Pearl
    Depart: Mon, Jan 17, 2022
    Returns: Fri, Jan 28, 2022
    Depart – Miami, Florida
    • At Sea
    • At Sea
    • Cartagena, Colombia
    • Panama Canal
    • Colon, Panama
    • Puerto Limon, Costa Rica
    • At Sea
    • Roatan, Honduras
    • Harvest Caye, Belize
    • Costa Maya, Mexico
    • At Sea
    Returns – Miami, Florida
    Miami, Florida - At Sea - At Sea - Cartagena, Colombia - Panama Canal - Colon, Panama - Puerto Limon, Costa Rica - At Sea - Roatan, Honduras - Harvest Caye, Belize - Costa Maya, Mexico - At Sea - Miami, Florida
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • Dash Sale! Up to $1000 Onboard Cash Credit - Ends 5/31
    • FREE Dining, Excursion Credit & WiFi
    • FREE Drinks, Dining, Excursion Credit & WiFi
    • show more 
    from
    $1,039* USD
    *restrictions apply
    Gov't fees & taxes from: $462/pp.
  • 8-Night Panama Canal Cruise

    up to
    $50
    CREDIT*
    8-Night Panama Canal Cruise
    Carnival Cruise Lines
    Carnival Legend
    Depart: Sat, Dec 12, 2020
    Returns: Sun, Dec 20, 2020
    Depart – Tampa, Florida
    • At Sea
    • At Sea
    • Puerto Limon, Costa Rica
    • Panama Canal
    • At Sea
    • Georgetown, Grand Cayman, Cayman Islands
    • At Sea
    Returns – Tampa, Florida
    Tampa, Florida - At Sea - At Sea - Puerto Limon, Costa Rica - Panama Canal - At Sea - Georgetown, Grand Cayman- At Sea - Tampa, Florida
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • Exlusive Reduced Deposit & $50 Credit- Ends 6/1
    • Early Saver Sale! Reduced Deposit - Ends 6/1
    • Great Rates
    from
    $669* USD
    *restrictions apply
    Gov't fees & taxes from: $345/pp.
  • 10-Night Panama Canal Cruise

    BEST
    VALUE*
    10-Night Panama Canal Cruise
    Holland America Line
    ms Zuiderdam
    Depart: Sun, Mar 28, 2021
    Returns: Wed, Apr 7, 2021
    Depart – Fort Lauderdale, Florida
    • Half Moon Cay, Bahamas
    • At Sea
    • Oranjestad, Aruba
    • Willemstad, Curacao, Netherlands Antilles
    • At Sea
    • Panama Canal
    • Gatun Lake, Panama
    • Panama Canal
    • Colon, Panama
    • Puerto Limon, Costa Rica
    • At Sea
    • At Sea
    Returns – Fort Lauderdale, Florida
    Fort Lauderdale, Florida - Half Moon Cay, Bahamas - At Sea - Oranjestad, Aruba - Willemstad, Curacao- At Sea - Panama Canal - Gatun Lake, Panama - Panama Canal - Colon, Panama - Puerto Limon, Costa Rica - At Sea - At Sea - Fort Lauderdale, Florida
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • Save Now, Cruise Later - FREE Drinks, Gratuities, Dining Package, and more on select rates
    • Limited Availability! Reduced Rates
    from
    $1,099* USD
    *restrictions apply
  • 15-Night Panama Canal Cruise

    BEST
    VALUE*
    15-Night Panama Canal Cruise
    Princess Cruises
    Coral Princess
    Depart: Fri, Oct 16, 2020
    Returns: Sat, Oct 31, 2020
    Depart – Los Angeles, California
    • At Sea
    • At Sea
    • Puerto Vallarta, Mexico
    • At Sea
    • Huatulco, Mexico
    • At Sea
    • San Juan del Sur, Nicaragua
    • Puntarenas, Costa Rica
    • At Sea
    • Fuerte Amador, Panama
    • Panama Canal
    • Cartagena, Colombia
    • At Sea
    • At Sea
    Returns – Fort Lauderdale, Florida
    Los Angeles, California - At Sea - At Sea - Puerto Vallarta, Mexico - At Sea - Huatulco, Mexico - At Sea - San Juan del Sur, Nicaragua - Puntarenas, Costa Rica - At Sea - Fuerte Amador, Panama - Panama Canal - Cartagena, Colombia - At Sea - At Sea - Fort Lauderdale, Florida
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • Princess Plus - FREE Drinks, Gratuities & Wi-Fi on select rates!
    • Receive a $60 Onboard Cash Credit per stateroom
    • Non Refundable Deposit on select rates
    from
    $1,349* USD
    *restrictions apply

Terms & Conditions

*Expedia Extras offers are per stateroom (unless otherwise stated) on select sailings, based on double occupancy, apply to new bookings only, are not combinable with any other offer, are capacity controlled and may be withdrawn without notice. Certain restrictions may apply. For full terms and conditions, click the specific Expedia Extra offer or contact your Expedia CruiseShipCenters Vacation Consultant.

Prices are per person (based on 2 passengers in the same stateroom), cruise only in USD dollars. Airfare, transfers, taxes, fees and port expenses are additional (unless otherwise stated). Prices vary by ship, stateroom type and sailing date. Prices and offers are subject to availability and change without notice, and are capacity controlled. Fuel supplement may apply. Expedia CruiseShipCenters is not responsible for errors that may occur due to the transfer of information from selected third parties, technical error, or human error.

Our default sort order is based on a number of relevant factors such as cruise line rating, ship rating, price per day, origin rating, destination rating, length of cruise, and booking window.

Our Promise


At Expedia CruiseShipCenters, we are navigators of spectacular vacation experiences. As part of the number one brand in travel, this is our promise to you:


Learn More 
  • Advice you can trust.

  • The best choice in prices.

  • Expedia Extras.

  • More than cruises.

  • Always there.


Expedia CruiseShipCenters
President's Circle - Platinum