There are lots of wonderful opportunities to cruise to and/or from Vancouver!
You may be interested in reading my blog post on this topic: Cruising to/from Vancouver
Below are some of my top picks:
June 17, 2019: Crystal Symphony (1111724) - sail Crystal from San Francisco to Vancouver
June 30, 2019: Queen Elizabeth - 24 nights from Vancouver to New York
August 6, 2019: Oceania Regatta (1039003) - 14-night roundtrip Alaska from Vancouver to Seattle
August 14, 2019: Viking Orion - Vancouver to Hong Kong
October 6, 2019: Norwegian Joy (1130619): 5 night coastal cruise on this brand new ship!
March 15, 2020: Koningsdam (1115292)- 48 night South America circle cruise from Fort Lauderdale to Vancouver!
April 4, 2020: Ruby Princess (1128265) - 34 nights from Sydney to Vancouver via New Zealand, American Samoa, Tahiti and Hawaii
April 12, 2020: Ruby Princess (1154527) - Auckland to Vancouver via the South Pacific
April 12, 2020: Maasdam (1146167) - 18 night Mexico cruise (unusual ports!) from San Diego to Vancouver
April 14, 2020: Oceania Regatta (1129658): 30 night sailing from Papeete (Tahiti) to Vancouver... via Alaska!
May 15, 2020: Pacific Princess (1157473): interesting 12 night Alaska cruise, roundtrip Vancouver (small ship, unique ports!)
July 2, 2020: Queen Elizabeth (1186137) - sail to San Francisco for July 4th on Cunard, roundtrip Vancouver
August 25, 2020: Golden Princess (1236890) - 29 night sailing from Vancouver to Singapore via Alaska, Japan, Taiwan, Hong Kong and Vietnam (or just book 17 nights to Japan)
September 22, 2020: Grand Princess (1235217) - 15 night Hawaii cruise sailing roundtrip Vancouver
September 26, 2020: Pacific Princess (1217620) - 29 night small ship South Pacific cruise from Vancouver (5 port days in Hawaii and 13 in French Polynesia)
October 7, 2020: Grand Princess (1232307) - 10 night Pacific Coastal sailing roundtrip Vancouver (overnight in San Francisco!)
October 17, 2020: Grand Princess (1238572) - 37 nights from Vancouver to Shanghai via San Francisco, Hawaii, Guam, Japan, Taiwan and South Korea **VERY UNIQUE**
March 25, 2021: Emerald Princess (1235223) - lovely 21 night Panama Canal sailing from Fort Lauderdale to Vancouver (lots of ports!)
April 20, 2021: Sun Princess (1236892) - 28 nights from Singapore to Vancouver via Vietnam, Hong Kong, Taiwan, Japan and Alaska
April 25, 2021: Celebrity Millennium (1150994) - the always popular Pacific Rim sailing
May 2, 2021: Sun Princess (1236896) - 16 nights from Tokyo to Vancouver
Note: I do tend to concentrate these picks on destinations other than Alaska (you'll find more Alaska sailings here).
Please contact me if you would like to explore more possibilities.