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  • Destinations
    South America
  • Departure Ports
    Any Port
  • Departure Date Range
    Any Date
  • Adults (25+)
    2

385 Cruises

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  • 5-Night South America Cruise

    5-Night South America Cruise
    MSC Cruises
    MSC Fantasia
    Depart: Fri, Dec 6, 2019
    Returns: Wed, Dec 11, 2019
    Depart – Rio de Janeiro, Brazil
    • IlhaBela, Brazil
    • At Sea
    • Punta del Este, Uruguay
    • Buenos Aires, Argentina
    Returns – Buenos Aires, Argentina
    Rio de Janeiro, Brazil - IlhaBela, Brazil - At Sea - Punta del Este, Uruguay - Buenos Aires, Argentina - Buenos Aires, Argentina
    from
    $1,312* CAD
    *restrictions apply
    Taxes of $94 Included


  • 6-Night South America Cruise

    6-Night South America Cruise
    MSC Cruises
    MSC Fantasia
    Depart: Sat, Dec 14, 2019
    Returns: Fri, Dec 20, 2019
    Depart – Rio de Janeiro, Brazil
    • Buzios, Brazil
    • At Sea
    • Salvador, Brazil
    • Ilheus, Brazil
    • At Sea
    Returns – Rio de Janeiro, Brazil
    Rio de Janeiro, Brazil - Buzios, Brazil - At Sea - Salvador, Brazil - Ilheus, Brazil - At Sea - Rio de Janeiro, Brazil
    from
    $995* CAD
    *restrictions apply
    Taxes of $112 Included
  • 3-Night South America Cruise

    3-Night South America Cruise
    MSC Cruises
    MSC Sinfonia
    Depart: Tue, Mar 10, 2020
    Returns: Fri, Mar 13, 2020
    Depart – Buenos Aires, Argentina
    • At Sea
    • At Sea
    Returns – Santos, Brazil
    Buenos Aires, Argentina - At Sea - At Sea - Santos, Brazil
    from
    $465* CAD
    *restrictions apply
    Taxes of $56 Included
  • 8-Night South America Cruise

    8-Night South America Cruise
    MSC Cruises
    MSC Fantasia
    Depart: Fri, Dec 6, 2019
    Returns: Sat, Dec 14, 2019
    Depart – Rio de Janeiro, Brazil
    • IlhaBela, Brazil
    • At Sea
    • Punta del Este, Uruguay
    • Buenos Aires, Argentina
    • Buenos Aires, Argentina
    • At Sea
    • At Sea
    Returns – Rio de Janeiro, Brazil
    Rio de Janeiro, Brazil - IlhaBela, Brazil - At Sea - Punta del Este, Uruguay - Buenos Aires, Argentina - Buenos Aires, Argentina - At Sea - At Sea - Rio de Janeiro, Brazil
    from
    $1,153* CAD
    *restrictions apply
    Taxes of $150 Included
  • 15-Night South America Cruise

    15-Night South America Cruise
    Celebrity Cruises
    Celebrity Eclipse
    Depart: Fri, Dec 6, 2019
    Returns: Sat, Dec 21, 2019
    Depart – San Antonio, Chile
    • At Sea
    • Puerto Montt, Chile
    • Chilean Fjords, Chile
    • Strait of Magellan, Chile
    • At Sea
    • Punta Arenas, Chile
    • Ushuaia, Argentina
    • Cape Horn, Chile
    • At Sea
    • Puerto Madryn, Argentina
    • At Sea
    • Punta del Este, Uruguay
    • Montevideo, Uruguay
    • Buenos Aires, Argentina
    Returns – Buenos Aires, Argentina
    San Antonio, Chile - At Sea - Puerto Montt, Chile - Chilean Fjords, Chile - Strait of Magellan, Chile - At Sea - Punta Arenas, Chile - Ushuaia, Argentina - Cape Horn, Chile - At Sea - Puerto Madryn, Argentina - At Sea - Punta del Este, Uruguay - Montevideo, Uruguay - Buenos Aires, Argentina - Buenos Aires, Argentina
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • Sail Your Way Savings Offer! Save up to $500 per stateroom!
    • Sail Plus! FREE Drinks & WiFi
    • Sail Plus! FREE Drinks & Tips
    • show more 
    from
    $1,839* CAD
    *restrictions apply
    Taxes of $376 Included
  • 7-Night South America Cruise

    7-Night South America Cruise
    MSC Cruises
    MSC Sinfonia
    Depart: Fri, Jan 10, 2020
    Returns: Fri, Jan 17, 2020
    Depart – Santos, Brazil
    • Itajai, Brazil
    • At Sea
    • Montevideo, Uruguay
    • Buenos Aires, Argentina
    • At Sea
    • At Sea
    Returns – Santos, Brazil
    Santos, Brazil - Itajai, Brazil - At Sea - Montevideo, Uruguay - Buenos Aires, Argentina - At Sea - At Sea - Santos, Brazil
    from
    $1,081* CAD
    *restrictions apply
    Taxes of $131 Included
  • 4-Night South America Cruise

    4-Night South America Cruise
    MSC Cruises
    MSC Fantasia
    Depart: Mon, Dec 2, 2019
    Returns: Fri, Dec 6, 2019
    Depart – Santos, Brazil
    • Rio de Janeiro, Brazil
    • At Sea
    • Ilha Grande, Brazil
    Returns – Rio de Janeiro, Brazil
    Santos, Brazil - Rio de Janeiro, Brazil - At Sea - Ilha Grande, Brazil - Rio de Janeiro, Brazil
    from
    $623* CAD
    *restrictions apply
    Taxes of $75 Included
  • 4-Night South America Cruise

    4-Night South America Cruise
    MSC Cruises
    MSC Seaview
    Depart: Tue, Feb 18, 2020
    Returns: Sat, Feb 22, 2020
    Depart – Santos, Brazil
    • Balneario Camboriu, Brazil
    • Porto Belo, Brazil
    • At Sea
    Returns – Santos, Brazil
    Santos, Brazil - Balneario Camboriu, Brazil - Porto Belo, Brazil - At Sea - Santos, Brazil
    from
    $837* CAD
    *restrictions apply
    Taxes of $75 Included
  • 7-Night South America Cruise

    7-Night South America Cruise
    MSC Cruises
    MSC Sinfonia
    Depart: Sat, Dec 21, 2019
    Returns: Sat, Dec 28, 2019
    Depart – Itajai, Brazil
    • At Sea
    • Montevideo, Uruguay
    • Buenos Aires, Argentina
    • At Sea
    • At Sea
    • Santos, Brazil
    Returns – Itajai, Brazil
    Itajai, Brazil - At Sea - Montevideo, Uruguay - Buenos Aires, Argentina - At Sea - At Sea - Santos, Brazil - Itajai, Brazil
    from
    $1,081* CAD
    *restrictions apply
    Taxes of $131 Included
  • 20-Night South America Cruise

    up to
    $600
    CREDIT*
    20-Night South America Cruise
    Holland America Line
    ms Amsterdam
    Depart: Tue, Sep 24, 2019
    Returns: Mon, Oct 14, 2019
    Depart – Vancouver, British Columbia
    • Victoria, British Columbia
    • At Sea
    • San Francisco, California
    • Monterey, California
    • Santa Barbara, California
    • San Diego, California
    • At Sea
    • Cabo San Lucas, Mexico
    • At Sea
    • At Sea
    • Huatulco, Mexico
    • At Sea
    • At Sea
    • Fuerte Amador, Panama
    • At Sea
    • Manta, Ecuador
    • At Sea
    • Salaverry, Peru
    • Callao, Peru
    Returns – Callao, Peru
    Vancouver, British Columbia - Victoria, British Columbia - At Sea - San Francisco, California - Monterey, California - Santa Barbara, California - San Diego, California - At Sea - Cabo San Lucas, Mexico - At Sea - At Sea - Huatulco, Mexico - At Sea - At Sea - Fuerte Amador, Panama - At Sea - Manta, Ecuador - At Sea - Salaverry, Peru - Callao, Peru - Callao, Peru
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • Oceans of Extras - Receive up to $600 Onboard Cash Credit!
    from
    $3,187* CAD
    *restrictions apply
    Taxes of $688 Included

Terms & Conditions

*Expedia Extras offers are per stateroom (unless otherwise stated) on select sailings, based on double occupancy, apply to new bookings only, are not combinable with any other offer, are capacity controlled and may be withdrawn without notice. Certain restrictions may apply. For full terms and conditions, click the specific Expedia Extra offer or contact your Expedia CruiseShipCenters Vacation Consultant.

Prices are per person (based on 2 passengers in the same stateroom), cruise only in CAD dollars. Airfare, transfers, taxes, fees and port expenses are additional (unless otherwise stated). Prices vary by ship, stateroom type and sailing date. Prices and offers are subject to availability and change without notice, and are capacity controlled. Fuel supplement may apply. Expedia CruiseShipCenters is not responsible for errors that may occur due to the transfer of information from selected third parties, technical error, or human error.

Our default sort order is based on a number of relevant factors such as cruise line rating, ship rating, price per day, origin rating, destination rating, length of cruise, and booking window.

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