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  • Destinations
    South America
  • Departure Ports
    Any Port
  • Departure Date Range
    Any Date
  • Adults (25+)
    2

536 Cruises

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  • 5-Night South America Cruise

    5-Night South America Cruise
    MSC Cruises
    MSC Fantasia
    Depart: Mon, Jan 13, 2020
    Returns: Sat, Jan 18, 2020
    Depart – Rio de Janeiro, Brazil
    • At Sea
    • Salvador, Brazil
    • Ilheus, Brazil
    • At Sea
    Returns – Rio de Janeiro, Brazil
    Rio de Janeiro, Brazil - At Sea - Salvador, Brazil - Ilheus, Brazil - At Sea - Rio de Janeiro, Brazil
    from
    $1,053* CAD
    *restrictions apply
    Taxes of $94 Included


  • 6-Night South America Cruise

    6-Night South America Cruise
    MSC Cruises
    MSC Preziosa
    Depart: Sun, Dec 13, 2020
    Returns: Sat, Dec 19, 2020
    Depart – Rio de Janeiro, Brazil
    • Buzios, Brazil
    • At Sea
    • Salvador, Brazil
    • Ilheus, Brazil
    • At Sea
    Returns – Rio de Janeiro, Brazil
    Rio de Janeiro, Brazil - Buzios, Brazil - At Sea - Salvador, Brazil - Ilheus, Brazil - At Sea - Rio de Janeiro, Brazil
    from
    $821* CAD
    *restrictions apply
    Taxes of $112 Included
  • 7-Night South America Cruise

    7-Night South America Cruise
    MSC Cruises
    MSC Sinfonia
    Depart: Mon, Jan 13, 2020
    Returns: Mon, Jan 20, 2020
    Depart – Montevideo, Uruguay
    • Buenos Aires, Argentina
    • At Sea
    • At Sea
    • Santos, Brazil
    • Itajai, Brazil
    • At Sea
    Returns – Montevideo, Uruguay
    Montevideo, Uruguay - Buenos Aires, Argentina - At Sea - At Sea - Santos, Brazil - Itajai, Brazil - At Sea - Montevideo, Uruguay
    from
    $1,050* CAD
    *restrictions apply
    Taxes of $131 Included
  • 3-Night South America Cruise

    3-Night South America Cruise
    MSC Cruises
    MSC Preziosa
    Depart: Tue, Mar 2, 2021
    Returns: Fri, Mar 5, 2021
    Depart – Santos, Brazil
    • Porto Belo, Brazil
    • Balneario Camboriu, Brazil
    Returns – Santos, Brazil
    Santos, Brazil - Porto Belo, Brazil - Balneario Camboriu, Brazil - Santos, Brazil
    from
    $445* CAD
    *restrictions apply
    Taxes of $56 Included
  • 3-Night South America Cruise

    3-Night South America Cruise
    MSC Cruises
    MSC Preziosa
    Depart: Sun, Mar 21, 2021
    Returns: Wed, Mar 24, 2021
    Depart – Santos, Brazil
    • Porto Belo, Brazil
    • Balneario Camboriu, Brazil
    Returns – Santos, Brazil
    Santos, Brazil - Porto Belo, Brazil - Balneario Camboriu, Brazil - Santos, Brazil
    from
    $445* CAD
    *restrictions apply
    Taxes of $56 Included
  • 3-Night South America Cruise

    3-Night South America Cruise
    MSC Cruises
    MSC Preziosa
    Depart: Wed, Mar 24, 2021
    Returns: Sat, Mar 27, 2021
    Depart – Santos, Brazil
    • Porto Belo, Brazil
    • Balneario Camboriu, Brazil
    Returns – Santos, Brazil
    Santos, Brazil - Porto Belo, Brazil - Balneario Camboriu, Brazil - Santos, Brazil
    from
    $495* CAD
    *restrictions apply
    Taxes of $56 Included
  • 7-Night South America Cruise

    7-Night South America Cruise
    MSC Cruises
    MSC Grandiosa
    Depart: Sat, Nov 28, 2020
    Returns: Sat, Dec 5, 2020
    Depart – Santos, Brazil
    • Buzios, Brazil
    • At Sea
    • Salvador, Brazil
    • Ilheus, Brazil
    • At Sea
    • Ilha Grande, Brazil
    Returns – Santos, Brazil
    Santos, Brazil - Buzios, Brazil - At Sea - Salvador, Brazil - Ilheus, Brazil - At Sea - Ilha Grande, Brazil - Santos, Brazil
    from
    $1,120* CAD
    *restrictions apply
    Taxes of $131 Included
  • 7-Night South America Cruise

    7-Night South America Cruise
    MSC Cruises
    MSC Sinfonia
    Depart: Mon, Jan 27, 2020
    Returns: Mon, Feb 3, 2020
    Depart – Montevideo, Uruguay
    • Buenos Aires, Argentina
    • At Sea
    • At Sea
    • Santos, Brazil
    • Itajai, Brazil
    • At Sea
    Returns – Montevideo, Uruguay
    Montevideo, Uruguay - Buenos Aires, Argentina - At Sea - At Sea - Santos, Brazil - Itajai, Brazil - At Sea - Montevideo, Uruguay
    from
    $1,050* CAD
    *restrictions apply
    Taxes of $131 Included
  • 14-Night South America Cruise

    BEST
    VALUE*
    14-Night South America Cruise
    Celebrity Cruises
    Celebrity Eclipse
    Depart: Sun, Feb 2, 2020
    Returns: Sun, Feb 16, 2020
    Depart – Buenos Aires, Argentina
    • At Sea
    • At Sea
    • At Sea
    • Ushuaia, Argentina
    • Cape Horn, Chile
    • Schollart Channel, Antarctica
    • Paradise Bay / Errera Channel, Antarctica
    • Gerlache Strait, Antarctica
    • South Shetland Islands, Antarctica
    • At Sea
    • Port Stanley, Falkland Islands (Malvinas)
    • At Sea
    • Puerto Madryn, Argentina
    • At Sea
    • Montevideo, Uruguay
    Returns – Buenos Aires, Argentina
    Buenos Aires, Argentina - At Sea - At Sea - At Sea - Ushuaia, Argentina - Cape Horn, Chile - Schollart Channel, Antarctica - Paradise Bay / Errera Channel, Antarctica - Gerlache Strait, Antarctica - South Shetland Islands, Antarctica - At Sea - Port Stanley, Falkland Islands (Malvinas) - At Sea - Puerto Madryn, Argentina - At Sea - Montevideo, Uruguay - Buenos Aires, Argentina
    Expedia® Extras* (Extras vary and apply to select staterooms and prices)
    • Book Now Bonus - Up to $200 Credit per person for up to 5 guests
    • Sail Plus! Beverage Package & WiFi
    • Sail Plus! Beverage Package & Tips
    • show more 
    from
    $2,235* CAD
    *restrictions apply
    Taxes of $381 Included
  • 7-Night South America Cruise

    7-Night South America Cruise
    MSC Cruises
    MSC Fantasia
    Depart: Sun, Jan 3, 2021
    Returns: Sun, Jan 10, 2021
    Depart – Santos, Brazil
    • At Sea
    • Montevideo, Uruguay
    • Buenos Aires, Argentina
    • Buenos Aires, Argentina
    • Punta del Este, Uruguay
    • At Sea
    Returns – Santos, Brazil
    Santos, Brazil - At Sea - Montevideo, Uruguay - Buenos Aires, Argentina - Buenos Aires, Argentina - Punta del Este, Uruguay - At Sea - Santos, Brazil
    from
    $1,100* CAD
    *restrictions apply
    Taxes of $131 Included

Terms & Conditions

*Expedia Extras offers are per stateroom (unless otherwise stated) on select sailings, based on double occupancy, apply to new bookings only, are not combinable with any other offer, are capacity controlled and may be withdrawn without notice. Certain restrictions may apply. For full terms and conditions, click the specific Expedia Extra offer or contact your Expedia CruiseShipCenters Vacation Consultant.

Prices are per person (based on 2 passengers in the same stateroom), cruise only in CAD dollars. Airfare, transfers, taxes, fees and port expenses are additional (unless otherwise stated). Prices vary by ship, stateroom type and sailing date. Prices and offers are subject to availability and change without notice, and are capacity controlled. Fuel supplement may apply. Expedia CruiseShipCenters is not responsible for errors that may occur due to the transfer of information from selected third parties, technical error, or human error.

Our default sort order is based on a number of relevant factors such as cruise line rating, ship rating, price per day, origin rating, destination rating, length of cruise, and booking window.

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